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The upcoming NCAAF showdown on December 6, 2025, features the Virginia Cavaliers hosting the Duke Blue Devils at Bank of America Stadium in Charlotte, NC. This Saturday football event promises intense action as both teams battle for supremacy in the 2025-26 season. Virginia enters as the favorite with a point spread of -3 -110, while Duke holds a +3 -109 underdog position. The opening point spread was the same, indicating steady confidence in Virginia's edge.
Betting odds also show Virginia favored on the moneyline at -148 versus Duke's +122, emphasizing Virginia's stronger position. The over/under total is set at 57.5, with the over at -114 and under at -107, signaling expectations of a moderately high-scoring game. Catch the game live on ABC and use these insights to inform your wagers.
These odds and betting lines help bettors gauge market sentiment and value, crucial for making smart bets. For more information on league-wide odds, check out the NCAAF odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Jacksonville State 8-429% -1½ -103Caesars | |||||||
![]() James Madison 11-150% -21½ -114FanDuel | |||||||
#24Tulane 10-254% +2½ -105BetMGM | |||||||
![]() Boise State 8-4100% -3½ -105Bet365 | |||||||
![]() #5Texas Tech 11-139% -13 -110Bet365 | |||||||
![]() Western Michigan 8-425% -2½ -110Bet365 | |||||||
#10Alabama 10-252% +2½ -104FanDuel | |||||||
![]() #18Virginia 10-228% -2½ -122FanDuel | |||||||
![]() #1Ohio State 12-064% -5½ -110Caesars |
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