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The Saturday football clash on November 29, 2025, between the Wake Forest Demon Deacons and Duke Blue Devils at Brooks Field at Wallace Wade Stadium in Durham, NC, promises an exciting ACC showdown. Duke enters as the home team with a slight edge in the odds, favored by 1.5 points with a total points line set at 53.5. This game will be broadcast on the ACC Network, giving fans nationwide access to the action.
Duke's offense averages 425.4 total yards per game, with a balanced attack featuring 291.3 passing yards and 134.1 rushing yards. Their defense is formidable, allowing just 316.8 total yards on average. Wake Forest counters with a solid offense gaining 381.9 total yards per game, including 222.3 passing and 159.6 rushing yards, while their defense concedes 409.4 yards. The quarterbacks for both teams are expected to start, with Duke's passing offense facing a tough Wake Forest pass rush and vice versa, setting up an intriguing battle of pass protection versus pass rush.
Wake Forest holds an 8-3 straight-up record and an impressive 8-3 against the spread, demonstrating strong betting trends and consistency. Duke, on the other hand, has a 6-5 straight-up record but struggles against the spread at 4-6-1. The previous matchup on November 30, 2024, saw Duke narrowly defeat Wake Forest 23-17, adding historical context to this rivalry.
With the point spread favoring Duke by 1.5 and an over/under of 53.5 points, bettors should consider the strong run offenses and defenses, as well as recent performances where both teams have shown scoring potential. These betting insights can guide smart wagering decisions for this ACC football game. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Don't forget to check out the details of their last matchup on November 30, 2024, which ended 23-17 in favor of Duke for further context.
West Virginia 4-773% +24½ -130BetMGM | |||||||
![]() Florida Atlantic 4-782% +7 -105BetMGM | |||||||
Louisville 7-415% -2½ -110Bet365 | |||||||
![]() South Carolina 3-732% -2½ -110Bet365 | |||||||
![]() #15Michigan 9-273% +10½ -122FanDuel | |||||||
![]() #22Pittsburgh 8-363% +7 -110Caesars | |||||||
Central Michigan 7-454% +11½ -115FanDuel | |||||||
Miami (OH) 6-550% -17½ -105Bet365 | |||||||
![]() Kansas State 5-635% -17 -110Bet365 | |||||||
Baylor 5-643% -2½ -114Caesars | |||||||
Oklahoma State 1-1081% +14 -110BetMGM | |||||||
![]() Delaware 5-630% -3½ -118FanDuel | |||||||
![]() Sam Houston State 2-971% +11½ -113BetRivers | |||||||
#11Brigham Young 10-166% -17½ -106FanDuel | |||||||
Marshall 5-622% -10 -110Bet365 | |||||||
![]() Old Dominion 8-327% -27½ -110Bet365 | |||||||
![]() Missouri State 7-429% -2½ -110Bet365 | |||||||
![]() Jacksonville State 7-427% +3 -115BetMGM | |||||||
Appalachian State 5-643% -1½ -102FanDuel | |||||||
Syracuse 3-840% +3 -108BetRivers | |||||||
![]() Tulsa 4-745% -8½ -110Bet365 | |||||||
Texas State 5-640% -8½ -115FanDuel | |||||||
![]() Louisiana 5-620% -8½ -114SugarHouse | |||||||
New Mexico State 4-767% -3½ -105BetMGM | |||||||
#19Tennessee 8-336% -2½ -112FanDuel | |||||||
![]() Duke 6-546% -1 -110Bet365 | |||||||
Rutgers 5-694% +14 -118BetRivers | |||||||
![]() #8Oklahoma 9-264% -10½ -110Bet365 | |||||||
![]() UTSA 6-537% -7 -120SugarHouse | |||||||
TCU 6-487% -3 -124BetRivers | |||||||
Southern Miss 7-450% -6 -118SugarHouse | |||||||
![]() Arkansas 2-980% +4 -112Caesars | |||||||
Minnesota 6-534% +2½ -115Caesars | |||||||
![]() Washington 8-373% +7 -110Bet365 | |||||||
![]() Liberty 4-779% +2½ -115SugarHouse | |||||||
![]() Coastal Carolina 6-587% +22 -109Caesars | |||||||
Florida 3-827% -½ -115SugarHouse | |||||||
![]() Washington State 5-647% -13 -115BetRivers | |||||||
![]() South Florida 8-35% -28 -107Caesars | |||||||
Michigan State 3-895% -3½ -114FanDuel | |||||||
![]() #18Virginia 9-219% -8 +100Bet365 | |||||||
![]() North Carolina State 6-524% -7 -110Caesars | |||||||
Auburn 5-682% +6 -113BetRivers | |||||||
#24Tulane 9-28% -29½ -115BetMGM | |||||||
Illinois 7-413% -7 -110Bet365 | |||||||
#17USC 8-242% -21½ -108FanDuel | |||||||
![]() California 6-548% +13½ -110Bet365 | |||||||
![]() Nevada 3-874% +7½ -110Bet365 | |||||||
![]() San Jose State 3-886% +3½ -109Caesars | |||||||
Stanford 4-778% +32½ -110BetMGM | |||||||
![]() Hawaii 7-417% -7½ -110Caesars | |||||||
![]() Massachusetts 0-1214 +14½ -110Bet365 | |||||||
Eastern Michigan 4-821 +10 -105BetMGM | |||||||
![]() Memphis 8-417 -3½ -112Caesars | |||||||
Buffalo 5-726 +7½ -120FanDuel | |||||||
![]() Mississippi State 5-719 +8 -127SugarHouse | |||||||
Nebraska 7-516 +6 +100Caesars | |||||||
![]() Northern Illinois 3-931 -4½ -115Bet365 | |||||||
![]() Kansas 5-721 +10½ -115Caesars | |||||||
![]() Colorado State 2-1021 +2½ -105FanDuel | |||||||
![]() #23Georgia Tech 9-39 +16½ -105BetMGM | |||||||
![]() New Mexico 9-323 +1½ -115BetMGM | |||||||
![]() North Texas 11-152 -20 -112SugarHouse | |||||||
![]() Utah State 6-624 +1½ -105FanDuel | |||||||
![]() #16Texas 9-327 +2½ +100Caesars | |||||||
![]() Purdue 2-103 +29 -113BetRivers | |||||||
![]() #20Arizona State 8-47 +2 -107Caesars |
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