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The upcoming Friday football game on November 28, 2025, features the Indiana Hoosiers visiting the Purdue Boilermakers at Ross-Ade Stadium in West Lafayette, IN. This NCAAF regular season Week 14 matchup promises exciting betting trends and game insights for bettors. Indiana enters this contest undefeated on the road with an 11-0 straight-up record and a 2-2 against-the-spread record away from home. Purdue, struggling with a 2-9 overall record and a 3-3 home ATS record, looks to leverage home-field advantage to turn their season around.
Quarterback play will be crucial, with Indiana's starting QB showing strong passing stats, averaging 259.6 passing yards per game, while Purdue's QB averages 215.3 passing yards. Indiana boasts a potent passing offense (11.4 first downs passing) versus Purdue's solid pass defense allowing 10.3 first downs passing. On the ground, Indiana's rushing attack is superior with 12.4 first downs rushing compared to Purdue's 9.4 allowed. Defensively, Indiana allows just 29.6 points per game while Purdue struggles more, conceding 43.5 points.
The odds heavily favor Indiana with a -28.5 point spread and a total points line set at 53.5, suggesting a likely high-scoring affair with Indiana as strong favorites. Purdue's defense faces pressure against Indiana's balanced offense, particularly in pass protection versus pass rush matchups. The best odds available today for Indiana is -28.5 -108 at Caesars and for Purdue +28.5 -112 at Caesars.
For bettors looking to capitalize on these betting trends, understanding the statistical edges and recent form is key. Indiana's consistent offensive production and strong ATS record on the road make them a smart pick. However, Purdue playing at home could keep the score closer, so consider the point spread carefully. Tune in to NBC for live coverage and explore our Start your OddsTrader Turbo subscription for deeper betting insights or place your wager with a trusted U.S. regulated sportsbook like Caesars.
In their last matchup on November 30, 2024, the Indiana Hoosiers crushed the Purdue Boilermakers 66-0 at Memorial Stadium, Bloomington, showing a dominant performance that sets the tone for this upcoming clash.
Buffalo 5-682% +7 -108Caesars | |||||||
![]() Mississippi State 5-680% +7½ -117Caesars | |||||||
Nebraska 7-471% +6½ -117SugarHouse | |||||||
![]() Northern Illinois 3-825% -5 -110Bet365 | |||||||
![]() Kansas 5-681% +10½ -108Caesars | |||||||
![]() Colorado State 2-977% +2½ -108BetRivers | |||||||
![]() #23Georgia Tech 9-236% +14½ -120FanDuel | |||||||
![]() New Mexico 8-385% +1½ -115Caesars | |||||||
![]() North Texas 10-130% -19½ -118FanDuel | |||||||
![]() Utah State 6-582% +3 -105BetMGM | |||||||
![]() #16Texas 8-385% +3 -127BetRivers | |||||||
![]() Purdue 2-988% +29½ -120BetMGM | |||||||
![]() #20Arizona State 8-354% +2 -115BetRivers | |||||||
West Virginia 4-793% +24½ -130BetMGM | |||||||
![]() Florida Atlantic 4-783% +7 -105BetMGM | |||||||
Louisville 7-44% -2½ -118FanDuel | |||||||
![]() South Carolina 3-727% -2½ -110Bet365 | |||||||
![]() #15Michigan 9-279% +10½ -122FanDuel | |||||||
![]() #22Pittsburgh 8-370% +7 -109Caesars | |||||||
Central Michigan 7-489% +11½ -115FanDuel | |||||||
Miami (OH) 6-550% -17½ -109Caesars | |||||||
![]() Kansas State 5-614% -16½ -110Bet365 | |||||||
Baylor 5-655% -2½ -114Caesars | |||||||
Oklahoma State 1-10100% +14 -110BetMGM | |||||||
![]() Delaware 5-60% -4 -110Caesars | |||||||
![]() Sam Houston State 2-983% +11½ -113BetRivers | |||||||
#11Brigham Young 10-185% -17½ -110Bet365 | |||||||
Marshall 5-611% -10 -115Bet365 | |||||||
![]() Old Dominion 8-340% -26½ -120BetMGM | |||||||
![]() Missouri State 7-412% -1 -110Bet365 | |||||||
![]() Jacksonville State 7-429% +3 -125BetRivers | |||||||
Appalachian State 5-650% -1½ -110Bet365 | |||||||
Syracuse 3-819% +3½ -124SugarHouse | |||||||
![]() Tulsa 4-70% -8½ -110Bet365 | |||||||
Texas State 5-667% -8½ -115FanDuel | |||||||
![]() Louisiana 5-667% -8½ -105BetMGM | |||||||
New Mexico State 4-760% -3½ -105BetMGM | |||||||
#19Tennessee 8-328% -2½ -118SugarHouse | |||||||
![]() Duke 6-565% +1½ -118FanDuel | |||||||
Rutgers 5-6100% +14 -118BetRivers | |||||||
![]() #8Oklahoma 9-274% -10½ -110Caesars | |||||||
![]() UTSA 6-533% -7 -120SugarHouse | |||||||
TCU 6-493% -3 -124BetRivers | |||||||
Southern Miss 7-480% -6 -120SugarHouse | |||||||
![]() Arkansas 2-987% +3 -113Caesars | |||||||
Minnesota 6-514% +2 -112BetRivers | |||||||
![]() Washington 8-380% +6½ -104Caesars | |||||||
![]() Liberty 4-780% +2½ -115SugarHouse | |||||||
![]() Coastal Carolina 6-580% +22 -112BetRivers | |||||||
Florida 3-80% PK -110Bet365 | |||||||
![]() Washington State 5-640% -13½ -105FanDuel | |||||||
![]() South Florida 8-30% -28 -110Bet365 | |||||||
Michigan State 3-899% -3½ -114FanDuel | |||||||
![]() #18Virginia 9-227% -8 -115BetRivers | |||||||
![]() North Carolina State 6-537% -7 -110Bet365 | |||||||
Auburn 5-682% +6 -113BetRivers | |||||||
#24Tulane 9-20% -29½ -115BetMGM | |||||||
Illinois 7-419% -7½ -105BetMGM | |||||||
#17USC 8-240% -21½ -110FanDuel | |||||||
![]() California 6-536% +13½ -110Bet365 | |||||||
![]() Nevada 3-889% +7½ -105BetMGM | |||||||
![]() San Jose State 3-883% +3½ -105FanDuel | |||||||
Stanford 4-779% +32½ -110BetMGM | |||||||
![]() Hawaii 7-425% -7½ -110Caesars | |||||||
![]() Massachusetts 0-1214 +14½ -110Bet365 | |||||||
Eastern Michigan 4-821 +10 -105BetMGM | |||||||
![]() Memphis 8-417 -3½ -112Caesars |
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