Cincinnati Bengals vs Buffalo Bills Betting Trends

The upcoming NFL regular season Week 14 game on December 7, 2025, features the Cincinnati Bengals visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Sunday football matchup offers exciting betting trends and game insights for bettors. Buffalo will rely on their star quarterback Josh Allen, who has been a major offensive force this season. Meanwhile, Cincinnati will counter with Joe Burrow, known for his precision passing and ability to lead the Bengals' offense.

Buffalo's offense is strong with 225.3 passing yards per game and 155.7 total rushing yards, while their defense allows 256.8 passing yards and 153.3 rushing yards on average. Cincinnati's offense averages 224.8 passing yards and 88.5 rushing yards per game, with a defense that allows 163.2 passing yards and 141.3 rushing yards. The Bills have a slight edge in both pass protection and run offense, while the Bengals have a solid pass rush and run defense.

The Bengals enter as underdogs with a +6 point spread and a total points line of 53.5, indicating a moderately high-scoring game. Buffalo is favored at -6 with odds of -112 at Caesars sportsbook. Injuries to key defensive players like Buffalo's Joey Bosa (out) and questionable status players like Spencer Brown may affect the game dynamics. Cincinnati also faces challenges with injured players like Trey Hendrickson ruled out.

Recent performances show Buffalo with a solid 8-4 record and a balanced 6-6 ATS record, while Cincinnati holds a 4-8 record and 5-7 ATS. The Bills have been strong at home with a 5-1 record, while the Bengals struggle on the road at 2-4. The matchup is being broadcast on FOX, providing fans and bettors the chance to catch all the action live.

For bettors looking for smart betting decisions, these betting trends and stats provide crucial insights into the strengths and weaknesses of each team, helping to evaluate the point spread and total points betting markets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. In their last matchup on November 5, 2023, which Cincinnati won 24-18, the Bengals edged out the Bills in a close contest, setting the stage for an intense rematch.