Nov 16, 2025 1:00 PM EST

Week 11

Tampa Bay

6-3

Buffalo

BUF

-5½ (-110)o47½ (-110)

CBS

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Tampa Bay Buccaneers vs Buffalo Bills Odds

Updated:Nov 13, 2025 1:26 AM EST

The upcoming NFL showdown on November 16, 2025, features the Tampa Bay Buccaneers visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Sunday football game is set to be a thrilling Week 11 regular-season matchup, broadcast live on CBS. Bettors can expect competitive odds as the Bills enter as favorites with a -5½ -115 point spread at Caesars, opening from a pick'em line, indicating a shift in betting sentiment favoring Buffalo's home advantage.

The betting lines offer valuable insights for those looking to place smart wagers. The Moneyline favors the Bills at -275, while the Buccaneers are priced at +215, highlighting the perceived strength of the Bills. The over/under is set at 48 points with the over at -112, suggesting a moderately high-scoring game. These betting odds reflect the teams' current form and potential strategies, providing bettors with a comprehensive view to make informed decisions.

Understanding the movement from opening to current odds is crucial as it signals where the public and sharp money are leaning. The Bills gaining a -5½ spread from an initial pick'em suggests confidence in their ability to cover at home. For those interested in detailed league-wide betting trends, visit the NFL odds page to explore more. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook like Caesars and profit off the edge.

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ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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Personalize your notifications and get updates on the teams, players or events you care about most. THU 11/138:15 PM N.Y. Jets 2-7 75% +13 -105BetMGM
New England 8-2 25% -12½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/169:30 AM Washington 3-7 33% +2½ +100Caesars
Miami 3-7 67% -2½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Green Bay 5-3-1 36% -7 -110Caesars
N.Y. Giants 2-8 64% +7 -104FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Tampa Bay 6-3 41% +5½ -107Caesars
Buffalo 6-3 59% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Cincinnati 3-6 35% +5½ -107Caesars
Pittsburgh 5-4 65% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Houston 4-5 22% -6 -110Bet365
Tennessee 1-8 78% +7 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Chicago 6-3 71% +3 -125BetMGM
Minnesota 4-5 29% -2½ -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM Carolina 5-5 80% +3½ -110FanDuel
Atlanta 3-6 20% -3½ -105Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/161:00 PM L.A. Chargers 7-3 54% -3 -105Caesars
Jacksonville 5-4 46% +3 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:05 PM Seattle 7-2 46% +3 -109Caesars
L.A. Rams 7-2 54% -3 -109BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:05 PM San Francisco 6-4 25% -3 +100Bet365
Arizona 3-6 75% +3 -102Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:25 PM Baltimore 4-5 15% -7½ -109Caesars
Cleveland 2-7 85% +8 -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/164:25 PM Kansas City 5-4 30% -3½ -110Bet365
Denver 8-2 70% +4 -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SUN 11/168:20 PM Detroit 6-3 27% +2½ +100Caesars
Philadelphia 7-2 73% -2½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. MON 11/178:15 PM Dallas 3-5-1 9% -3½ -102BetMGM
Las Vegas 2-7 91% +3½ -114Caesars

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