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Nov 16, 2025 8:20 PM EST
Week 11
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-2½ (-120)o46½ (-110)
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Detroit Lions vs Philadelphia Eagles Picks
Updated:Nov 13, 2025 1:43 AM EST
The upcoming NFL showdown between the Detroit Lions and Philadelphia Eagles is set for November 17, 2025, at Lincoln Financial Field in Philadelphia, PA. This Sunday night football game is a must-watch for fans and bettors alike, airing on NBC and Peacock. Our expert picks have the Detroit Lions edging out the Eagles with a predicted score of 25 to 23, favoring Detroit at +2.5 on the point spread. The game is also expected to go just over the total of 46.5 points, with a predicted total score around 47.5.
Our prediction model has been profitable recently, boasting a hit rate of 56.7% on point spread bets, which is a high EV market for bettors. This strong track record, especially on spreads, gives bettors a smart edge when placing their bets. With both teams showing competitive form, our picks and betting tips offer valuable insights to help you make informed wagers. Whether you’re looking to place straight bets or parlays, this game offers plenty of betting opportunities.
Don’t miss out on the action or expert NFL picks; check out the detailed predictions for this and other games in the league on our NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
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NFLWeek 11
 New England 8-225% -12½ -118FanDuel | |||||||
 Miami 3-767% -2½ -115Bet365 | |||||||
 N.Y. Giants 2-864% +7 -104FanDuel | |||||||
 Buffalo 6-359% -5½ -110Bet365 | |||||||
 Pittsburgh 5-465% -5½ -110Bet365 | |||||||
 Tennessee 1-878% +7 -117SugarHouse | |||||||
 Minnesota 4-529% -2½ -115Caesars | |||||||
 Atlanta 3-620% -3½ -105Bet365 | |||||||
 Jacksonville 5-446% +3 -114BetRivers | |||||||
 L.A. Rams 7-254% -3 -109BetRivers | |||||||
 Arizona 3-675% +3 -102Caesars | |||||||
 Cleveland 2-785% +8 -117SugarHouse | |||||||
 Denver 8-270% +4 -114BetRivers | |||||||
 Philadelphia 7-273% -2½ -114FanDuel | |||||||
 Las Vegas 2-791% +3½ -114Caesars |
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