The CFP rankings are now released weekly as the season winds down, and we begin focusing on our college football conference winner predictions.
But if we peer into our crystal ball and gaze even further down the road, we are looking at the college football national championship odds and which teams are worth our betting buck.
2025-26 College Football Championship Odds
The top 12 teams will compete for the national college football championship, but there are still a few more regular-season games and, of course, college football conference championships. Therefore, much can happen between now and then, but after the most recent round of CFP rankings, we’ve got a favorite, a possible contender, and a sleeper that has caught our eye.
Ohio State (+185)
The Buckeyes are the favorite for a reason.
They last felt the sting of a loss when they played their archrival, Michigan, in their 2024 regular season finale, nicknamed The Game. But Ohio State would roll in the CFP, defeating Tennessee, Oregon, Texas, and Notre Dame to claim the natty.
This season has been a continuation of the Buckeyes’ dominance. Ohio State is undefeated and is 8-1-1 against the spread. Not only are they winning, but they are also doing it convincingly while making oodles of money for their backers.
I realize +185 is not a great return, but it beats losing.
Alabama (+1300)
You know there is a changing of the guard in college football when perennial powerhouse Alabama is a middle-of-the-road pick.
However, as an old coach once said, “You are what your record says you are.” And in this case, the Crimson Tide are a rather surprising 8-2 as the season enters the final stretch.
In their last outing, Alabama welcomed the Sooners to Tuscaloosa, and it didn’t turn out as planned. Although Alabama was installed as a 6 ½ point home chalk, the oddsmakers had the wrong favorite, as Oklahoma shocked the Bama faithful and strutted out with a 23-21 victory.
Nevertheless, Alabama has a solid quarterback in Ty Simpson and an excellent passing attack bolstered by a superior defense. However, what this edition is lacking is a rushing game.
They have become too predictable on offense, and that has caused them to lose to both Florida State in their season opener and to the Sooners last week. Yet, this is a program designed to win championships.
I believe that the college football national championship odds of +1300 are well worth the money.
Oklahoma (+2000)
Oklahoma is ranked No. 8 in the country after defeating the Alabama Crimson Tide.
Yet, the college national championship football odds are among the highest of the eligible schools at +2000. Well, if the oddsmakers are going to be generous, who am I to refuse their largesse?
The Sooners just invaded one of the most hostile environments in college football and came out with a victory. That’s a very good team and one that could very well wrest the national championship for a school that hasn’t won a natty since the turn of the new millennium.
Oklahoma has always been known for having an explosive offense, but this season, the tables have turned. The Sooners’ defense is the star of the show, while the offense is barely more than serviceable. Yet, they have a knack for getting critical first downs and moving the chains.
Is this a team of destiny at odds of +2000? Sure, why not?!
Place Your College Football National Championship Picks & Have Multiple Sportsbooks
After we make our college football conference winner predictions and review the college national championship odds, we need to remember that the lines you see here at OddsTrader don’t stay stagnant.
These prices are dynamic and will move as soon as enough money comes in on them. Therefore, it is important that you get the sharpest line available, and the only way to do that is to get down immediately on the games and make sure you have an active account.
That’s right, make sure your account is funded, and consider opening accounts at two or more sportsbooks so you can compare the numbers. Make sure to get down at a place you trust and at the best lines or odds available.
While you’re at it, make sure to download the free-to-use OddsTrader App available for iOS and Android phones for odds, picks, and props anywhere at any time! Speaking of which, you can always check out all the college football national championship odds and player props on OddsTrader.
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