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The upcoming MLB regular season game between the Boston Red Sox and Houston Astros is scheduled for April 1, 2026, at 8:10 PM ET at Daikin Park in Houston, TX. Broadcasted on NESN, this game features a closely matched predicted score with Boston at 4.52 and Houston at 4.49 runs. Houston, favored with a 1.5-point spread and a 64.9% probability to cover, benefits from a retractable dome environment, potentially influencing gameplay. Our picks and betting tips favor Houston on the moneyline with a predicted final score of 5-4. Our prediction model has shown a strong hit rate over the last 10 games, particularly in spread bets, offering valuable insights for bettors. For more detailed analysis, visit our MLB picks page.
BALZ. Eflin (R) 2-2- +115Bookmaker | |||||||
PHIA. Painter (R) 1-30% -175BetOnline | |||||||
CINB. Williamson (L) 3-1- +103Everygame | |||||||
MIAJ. Junk (R) 3-133% -145Everygame | |||||||
![]() TORM. Scherzer (R) 3-10% -255BetOnline | |||||||
ATLJ. Suarez (L) 3-125% -145Everygame | |||||||
![]() CHCJ. Taillon (R) 2-20% -136BetOnline | |||||||
MILB. Woodruff (R) 3-133% -128BetOnline | |||||||
STLA. Pallante (R) 2-2100% +150Bookmaker | |||||||
HOUH. Brown (R) 3-250% -143BetOnline | |||||||
![]() SDG. Márquez (R) 1-30% +125Everygame | |||||||
SEAL. Gilbert (R) 3-2100% +103Everygame | |||||||
![]() AZB. Pfaadt (R) 1-30% -106MyBookie | |||||||
LADS. Ohtani (R) 3-10% -240BetOnline | |||||||
PHIC. Sánchez (L) 1-3- -190Bookmaker | |||||||
HOUM. Burrows (R) 3-2- -150Bookmaker | |||||||
![]() CHCM. Boyd (L) 2-2- -141Bookmaker | |||||||
![]() AZZ. Gallen (R) 1-3- -111Bookmaker | |||||||
![]() SDN. Pivetta (R) 1-3- +125Bookmaker | |||||||
SEAG. Kirby (R) 3-2- -104Bookmaker | |||||||
LADY. Yamamoto (R) 3-1- -270Bookmaker |