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The upcoming MLB game on March 21, 2026, features the Chicago Cubs visiting the Seattle Mariners at Peoria Sports Complex in Peoria, AZ. This matchup presents intriguing betting opportunities as both teams have shown varied performance against right-handed pitchers, which will influence hitting outcomes. Our picks and betting tips favor the Mariners with a predicted score of 5-3, supported by a positive EV and a cover percentage hit rate above 60% in recent games. The game will be broadcast on Seam TV, providing ample viewing access. For comprehensive analysis, visit our MLB picks page.
TBUndecided - +115BetOnline | |||||||
STLUndecided - -108Bookmaker | |||||||
BALUndecided - -130BetOnline | |||||||
![]() DETF. Valdez (L) - -124Bovada | |||||||
BOSG. Crochet (L) - -125Bovada | |||||||
PITP. Skenes (R) - -131Bovada | |||||||
LADE. Sheehan (R) - -197MyBookie | |||||||
KCC. Ragans (L) - -155BetOnline | |||||||
SFR. Ray (L) - -117Bovada | |||||||
![]() AZR. Nelson (R) - -104Bookmaker | |||||||
MILR. Gasser (L) - +100Bookmaker | |||||||
CINA. Abbott (L) - -131Bovada | |||||||
SEAUndecided - -115BetOnline |