- Run Line
- Money
- Total
- Merged
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May 6, 2026 3:45 PM EDT
SD
-108o8½ (-119)
NBCS-BA, NBCSBAMATCHUP
PREDICTION
ODDS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
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San Diego Padres vs San Francisco Giants Picks
Updated:May 6, 2026 2:06 AM EDT
The MLB regular season game between the San Diego Padres and San Francisco Giants is scheduled for May 6, 2026, at Oracle Park in San Francisco, CA. Broadcasted on nbcs-ba, this matchup features a predicted close contest with San Diego favored to cover a -1.5 spread with a 62.4% hit rate. Our picks and betting tips suggest a predicted score of 4.01 for San Francisco and 3.68 for San Diego, with an expected total under 8.5 runs. Our prediction model has been profitable recently, winning 6 of the last 10 point spread bets, indicating positive EV for bettors.
Hitters' performance against right-handed pitchers will be critical as both teams adjust to starting pitching. For detailed MLB analysis and more picks, visit our MLB picks and predictions page.
UPCOMING GAME PREDICTION
Run Line
Money
Total
SFMoney
CONSENSUS LINE
-106
PROJECTION
SD (3.8) - SF (4.0)
COVER PROBABILITY
EXPECTED VALUE
+4.2%
BET RATING
SEASON COVER %
14/36
39%
OTHER BETS
Wed 05/06 3:45 PMSD @ SF
Fernando TatisTotal Bases
EV
+20.6%
+20.6%
Xander BogaertsPlayer to hit a RBI
EV
+12.7%
+12.7%
Jesus RodriguezPlayer to hit a RBI
EV
+11.4%
+11.4%
Ramón LaureanoPlayer to hit a RBI
EV
+7.9%
+7.9%
Manny MachadoTotal Bases
EV
+7.2%
+7.2%
Rafael DeversTotal Bases
EV
+6.1%
+6.1%
Jung Hoo LeeTotal Bases
EV
+6.1%
+6.1%
Manny MachadoPlayer to hit a RBI
EV
+5.5%
+5.5%
Heliot RamosPlayer to hit a RBI
EV
+5.3%
+5.3%
MLB
Money
Game
- Game
- 1st 5
MLBWed 05/06
 TBS. McClanahan (L) 23-1221% -135Everygame | |||||||
 STLA. Pallante (R) 21-14- -105Everygame | |||||||
 HOUL. McCullers (R) 15-2283% +190Everygame | |||||||
 SFA. Houser (R) 14-220% +101Everygame | |||||||
 LAAW. Ureña (R) 14-2325% +100Everygame | |||||||
 SEAB. Woo (R) 17-2050% -128Bet105 | |||||||
 DETJ. Flaherty (R) 18-1967% -113BetOnline | |||||||
 MIAE. Pérez (R) 16-2033% -123BetOnline | |||||||
 PHIZ. Wheeler (R) 16-200% -168Everygame | |||||||
 WSHM. Mikolas (R) 16-2083% +125Everygame | |||||||
 NYYW. Warren (R) 25-110% -190BetOnline | |||||||
 CHCC. Rea (R) 24-1214% -169MyBookie | |||||||
 KCC. Ragans (L) 17-1940% -128Everygame | |||||||
 COLM. Lorenzen (R) 14-22100% +150Everygame | |||||||
 AZM. Soroka (R) 17-1762% +133Everygame | |||||||
COLJ. Quintana (L) 14-2265% +145Everygame |
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