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The upcoming Saturday football clash on November 22, 2025, features the Houston Cougars hosting the TCU Horned Frogs at TDECU Stadium in Houston, TX. This NCAAF regular season Week 13 game is set to be a thrilling encounter for fans and bettors alike. Houston Cougars have shown strong performance in their recent games, boasting a profitable prediction record in the last 10 games with wins in key markets such as the 2way and point spread bets. TCU Horned Frogs, meanwhile, have had mixed results but remain a formidable opponent with a competitive edge at home.
Our picks and betting tips favor Houston Cougars to win with a predicted score of 27-24, covering the spread with a -3.5 advantage. The prediction model has been profitable recently with a hit rate of over 60% in similar markets, providing bettors with an edge. This matchup will be broadcasted live, giving fans the chance to watch the game unfold and make informed bets.
For those looking to dive deeper into NCAAF picks, our comprehensive NCAAF picks and predictions page offers detailed insights and expert analysis. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Ohio 6-425% -32½ -108Caesars | |||||||
Bowling Green 3-70% -3½ -110FanDuel | |||||||
![]() Northern Illinois 3-750% +7½ -115FanDuel | |||||||
Buffalo 5-533% -2½ -108Caesars | |||||||
![]() Kent State 4-6100% +8 -108Caesars | |||||||
Arkansas State 5-50% -3 -110Caesars | |||||||
![]() North Carolina State 5-550% +5 -110BetMGM | |||||||
UNLV 8-20% -2½ -113BetRivers | |||||||
![]() #1Ohio State 10-00% -32½ -115FanDuel | |||||||
Army 5-4- -10½ -110BetMGM | |||||||
![]() Wake Forest 7-30% -17½ -110Bet365 | |||||||
Virginia Tech 3-7100% +17 -109BetRivers | |||||||
![]() #11Oklahoma 8-225% -8½ -115FanDuel | |||||||
SMU 7-322% -3 -115Caesars | |||||||
![]() Iowa State 6-4- -3½ -110FanDuel | |||||||
![]() Northwestern 5-5- -4½ -110BetMGM | |||||||
#3Texas A&M 10-0- - | |||||||
![]() #5Georgia 9-10% -43½ -110BetRivers | |||||||
![]() Georgia Southern 5-5100% +10½ -114BetRivers | |||||||
![]() James Madison 9-1100% -12½ -115FanDuel | |||||||
![]() Arizona 7-3100% -5½ -115FanDuel | |||||||
![]() Toledo 6-4- -26½ -110BetMGM | |||||||
Wyoming 4-6- -6½ -110Bet365 | |||||||
![]() Kennesaw State 7-3- -6 -113BetRivers | |||||||
#4Alabama 8-2- - | |||||||
Auburn 4-6- - | |||||||
Appalachian State 4-6100% +3½ -105FanDuel | |||||||
![]() Florida Atlantic 4-6100% +7½ -110FanDuel | |||||||
![]() UTEP 2-8- -3 -110BetMGM | |||||||
![]() Middle Tennessee 1-9100% -6½ -110FanDuel | |||||||
![]() Louisiana Tech 5-50% -1½ -102Caesars | |||||||
UAB 3-7- +21½ -115BetRivers | |||||||
![]() North Carolina 4-6100% +6½ -104FanDuel | |||||||
![]() #10Texas 7-30% -9½ -122FanDuel | |||||||
![]() #8Oregon 9-140% -8½ -110SugarHouse | |||||||
#21Iowa 6-4100% -16½ -110Bet365 | |||||||
![]() UTSA 5-5100% +3½ -113SugarHouse | |||||||
![]() #14Vanderbilt 8-233% -9½ -110BetMGM | |||||||
![]() South Alabama 3-7100% +3 -110Bet365 | |||||||
![]() Florida International 5-5- -1 -110Bet365 | |||||||
#9Notre Dame 8-2- -35 -110Bet365 | |||||||
Temple 5-5100% +8½ -114BetRivers | |||||||
UCF 4-6- -14½ -109Caesars | |||||||
Maryland 4-6100% +13½ -108Caesars | |||||||
![]() Houston 8-20% -2½ -106FanDuel | |||||||
![]() #13Utah 8-20% -16½ -115Bet365 | |||||||
Troy 6-4- -11½ -108Caesars | |||||||
![]() South Carolina 3-7- -23 -113Caesars | |||||||
![]() Clemson 5-5- - | |||||||
Texas State 4-6- -18½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-10% -2½ -110Bet365 | |||||||
![]() Penn State 4-60% -9½ -106Caesars | |||||||
![]() Boise State 6-4- -16½ -109BetRivers | |||||||
Air Force 3-7100% +2½ -110Bet365 | |||||||
Florida 3-7100% +3½ -110BetMGM | |||||||
Stanford 3-7100% +3 -107BetRivers | |||||||
![]() Wisconsin 3-7100% +9½ -105FanDuel | |||||||
Rice 5-5- +18½ -110BetMGM | |||||||
LSU 6-4- -21½ -110Bet365 | |||||||
![]() #25Cincinnati 7-3100% +2½ -106FanDuel | |||||||
![]() Colorado 3-7- +8½ -110FanDuel | |||||||
UCLA 3-7100% +10½ -105Caesars | |||||||
San Diego State 8-20% -10½ -109BetRivers | |||||||
![]() Fresno State 7-30% -2½ -110BetMGM |
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