Week 5 of the NFL season kicks off on Thursday, October 5, with the Bears facing the Commanders in Washington, D.C.
This week also marks the beginning of bye weeks, with four teams taking a break. The Cleveland Browns, Los Angeles Chargers, Seattle Seahawks, and Tampa Bay Buccaneers will rest.
Sunday brings us an exciting 12+ hour football marathon, starting with the Jaguars and the Bills in London at 9:30 AM ET. It promises to be an electric matchup.
Meanwhile, back in the United States, the 1 PM slate offers intriguing games. The Ravens visit the Steelers, and the Giants head to Miami to face the Dolphins.
In the late afternoon window, fans and bettors will be treated to the Chiefs taking on the Vikings, and the Jets joining the Mile High club in Denver.
However, the highlight of the week comes during Sunday Night Football, featuring another edition of the Cowboys vs. 49ers rivalry, this time in the Bay Area. The Packers also enter the prime-time spotlight as they visit Las Vegas to play the Raiders.
NFL Week 5 Odds
For the complete list of NFL Week 5 odds, refer to the information below.
|Bears vs. Commanders||Thursday, October 05||08:15 PM ET||Commanders -6.5 (-110)||44.5|
|Jaguars vs. Bills (London)||Sunday, October 8||09:30 AM ET||Bills -5.5 (-110)||48.5|
|Titans vs. Colts||Sunday, October 8||01:00 PM ET||Colts PK (-110)||42.5|
|Texans vs. Falcons||Sunday, October 8||01:00 PM ET||Falcons -2 (-110)||41.5|
|Panthers vs. Lions||Sunday, October 8||01:00 PM ET||Lions -9 (-110)||45|
|Ravens vs. Steelers||Sunday, October 8||01:00 PM ET||Ravens -3.5 (-110)||38|
|Saints vs. Patriots||Sunday, October 8||01:00 PM ET||Patriots -1.5 (-110)||40|
|Giants vs. Dolphins||Sunday, October 8||01:00 PM ET||Dolphins -11 (-110)||50|
|Eagles vs. Rams||Sunday, October 8||01:00 PM ET||Eagles -4 (-110)||50.5|
|Bengals vs. Cardinals||Sunday, October 8||04:05 PM ET||Bengals -3 (-110)||44.5|
|Jets vs. Broncos||Sunday, October 8||04:25 PM ET||Broncos – (-110)||43.5|
|Chiefs vs. Vikings||Sunday, October 8||04:25 PM ET||Chiefs -5 (-110)||53|
|Cowboys vs. 49ers||Sunday, October 8||08:20 PM ET||49ers -4 (-110)||45|
|Packers vs. Raiders||Monday, October 9||08:15 PM ET||Packers -2 (-110)||44.5|
Best NFL Week 5 Spread Available
|Matchup||Current Best Spread Available|
|Bears vs. Commanders||Commanders -6.5 (-110) at Caesars Sportsbook|
|Jaguars vs. Bills (London)||Bills -5.5 (-110) at Caesars Sportsbook|
|Titans vs. Colts||Colts PK (-110) at Caesars Sportsbook|
|Texans vs. Falcons||Falcons -2 (-109) at SugarHouse|
|Panthers vs. Lions||Lions -9 (-110) at Caesars Sportsbook|
|Ravens vs. Steelers||Ravens -3.5 (-110) at Caesars Sportsbook|
|Saints vs. Patriots||Patriots -1.5 (-110) at Caesars Sportsbook|
|Giants vs. Dolphins||Dolphins -11 (-110) at SBK|
|Eagles vs. Rams||Eagles -4 (-110) at Caesars Sportsbook|
|Bengals vs. Cardinals||Bengals -3 (-110) (-110) at Caesars Sportsbook|
|Jets vs. Broncos||Broncos -1.5 (-110) at SugarHouse|
|Chiefs vs. Vikings||Chiefs -5 (-110) at Caesars Sportsbook|
|Cowboys vs. 49ers||49ers -3.5 (-108) at BetRivers|
|Packers vs. Raiders||Packers -1.5 (-112) at SBK|
More Weekly NFL Odds Previews
Eager to explore the upcoming NFL schedule for the most recent odds or curious about the odds of a game that has already taken place? Check out our odds preview covering all 18 weeks of the NFL regular season!
- Week 1 Odds
- Week 2 Odds
- Week 3 Odds
- Week 4 Odds
- Week 6 Odds
- Week 7 Odds
- Week 8 Odds
- Week 9 Odds
- Week 10 Odds
- Week 11 Odds
- Week 12 Odds
- Week 13 Odds
- Week 14 Odds
- Week 15 Odds
- Week 16 Odds
- Week 17 Odds
- Week 18 Odds
*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.