Week 5 of the NFL season kicks off on Thursday, October 5, with the Bears facing the Commanders in Washington, D.C.
This week also marks the beginning of bye weeks, with four teams taking a break. The Cleveland Browns, Los Angeles Chargers, Seattle Seahawks, and Tampa Bay Buccaneers will rest.
Sunday brings us an exciting 12+ hour football marathon, starting with the Jaguars and the Bills in London at 9:30 AM ET. It promises to be an electric matchup.
Meanwhile, back in the United States, the 1 PM slate offers intriguing games. The Ravens visit the Steelers, and the Giants head to Miami to face the Dolphins.
In the late afternoon window, fans and bettors will be treated to the Chiefs taking on the Vikings, and the Jets joining the Mile High club in Denver.
However, the highlight of the week comes during Sunday Night Football, featuring another edition of the Cowboys vs. 49ers rivalry, this time in the Bay Area. The Packers also enter the prime-time spotlight as they visit Las Vegas to play the Raiders.
NFL Week 5 Odds
For the complete list of NFL Week 5 odds, refer to the information below.
| Matchup | Date | Time | Spread | Over/Under |
|---|---|---|---|---|
| Buccaneers vs. Falcons | Thursday, October 03 | 08:15 PM ET | Falcons -3 (-120) | 45.5 |
| Jets vs. Vikings (London) | Sunday, October 06 | 09:30 AM ET | Jets -3.5 (-115) | 43.5 |
| Browns vs. Commanders | Sunday, October 06 | 01:00 PM ET | Browns -3.5 (-115) | 44 |
| Ravens vs. Bengals | Sunday, October 06 | 01:00 PM ET | Bengals -1.5 (-120) | 46.5 |
| Bills vs. Texans | Sunday, October 06 | 01:00 PM ET | Texans -1 (-120) | 47.5 |
| Colts vs. Jaguars | Sunday, October 06 | 01:00 PM ET | Jaguars -1 (-120) | 47.5 |
| Panthers vs. Bears | Sunday, October 06 | 01:00 PM ET | Bears -5.5 (-120) | 42.5 |
| Dolphins vs. Patriots | Sunday, October 06 | 01:00 PM ET | Dolphins -6 (-120) | 45.2 |
| Cardinals vs. 49ers | Sunday, October 06 | 04:05 PM ET | 49ers -9.5 (-120) | 47.5 |
| Raiders vs. Broncos | Sunday, October 06 | 04:05 PM ET | Broncos -1.5 (-120) | 42 |
| Packers vs. Rams | Sunday, October 06 | 04:25 PM ET | Packers -1 (-120) | 48 |
| Giants vs. Seahawks | Sunday, October 06 | 04:25 PM ET | Seahawks -3 (-120) | 44.5 |
| Cowboys vs. Steelers | Sunday, October 06 | 08:20 PM ET | Cowboys -2.5 (-120) | 44.5 |
| Saints vs. Chiefs | Monday, October 07 | 08:15 PM ET | Chiefs -7.5 (-120) | 45 |
*Odds via Caesars Sportsbook (check our Caesars Sportsbook Review)
Best NFL Week 5 Spread Available
| Matchup | Current Best Spread Available |
|---|---|
| Buccaneers vs. Falcons | Falcons -3 (-120) at Caesars Sportsbook |
| Jets vs. Vikings (London) | Jets -3.5 (-115) at Bet365 |
| Browns vs. Commanders | Browns -3.5 (-115) at Caesars Sportsbook |
| Ravens vs. Bengals | Bengals -1.5 (-120) at Caesars Sportsbook |
| Bills vs. Texans | Ravens -3.5 (-110) at Caesars Sportsbook |
| Colts vs. Jaguars | Jaguars -1 (-120) at Caesars Sportsbook |
| Panthers vs. Bears | Bears -5.5 (-120) at Caesars Sportsbook |
| Dolphins vs. Patriots | Dolphins -6 (-120) at Caesars Sportsbook |
| Cardinals vs. 49ers | 49ers -9.5 (-120) at Caesars Sportsbook |
| Raiders vs. Broncos | Broncos -1.5 (-120) at Caesars Sportsbook |
| Packers vs. Rams | Packers -1 (-120) at Caesars Sportsbook |
| Giants vs. Seahawks | Seahawks -3 (-120) at Caesars Sportsbook |
| Cowboys vs. Steelers | Cowboys -2.5 (-120) at Caesars Sportsbook |
| Saints vs. Chiefs | Chiefs -7.5 (-120) at Caesars Sportsbook |
More Weekly NFL Odds Previews
Eager to explore the upcoming NFL schedule for the most recent odds or curious about the odds of a game that has already taken place? Check out our odds preview covering all 18 weeks of the NFL regular season!
- Week 1 Odds
- Week 2 Odds
- Week 3 Odds
- Week 4 Odds
- Week 6 Odds
- Week 7 Odds
- Week 8 Odds
- Week 9 Odds
- Week 10 Odds
- Week 11 Odds
- Week 12 Odds
- Week 13 Odds
- Week 14 Odds
- Week 15 Odds
- Week 16 Odds
- Week 17 Odds
- Week 18 Odds
*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.
