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NFL Week 5 Odds & Best Lines Available

Dak Prescott Dallas Cowboys NFL quarterback
Dak Prescott 4 of the Dallas Cowboys throws a pass against the San Francisco 49ers during the first quarter in the NFC Divisional Playoff game at Levis Stadium on January 22 2023 Thearon W HendersonGetty ImagesAFP


Week 5 of the NFL season kicks off on Thursday, October 5, with the Bears facing the Commanders in Washington, D.C.

This week also marks the beginning of bye weeks, with four teams taking a break. The Cleveland Browns, Los Angeles Chargers, Seattle Seahawks, and Tampa Bay Buccaneers will rest.

Sunday brings us an exciting 12+ hour football marathon, starting with the Jaguars and the Bills in London at 9:30 AM ET. It promises to be an electric matchup.

Meanwhile, back in the United States, the 1 PM slate offers intriguing games. The Ravens visit the Steelers, and the Giants head to Miami to face the Dolphins.

In the late afternoon window, fans and bettors will be treated to the Chiefs taking on the Vikings, and the Jets joining the Mile High club in Denver.

However, the highlight of the week comes during Sunday Night Football, featuring another edition of the Cowboys vs. 49ers rivalry, this time in the Bay Area. The Packers also enter the prime-time spotlight as they visit Las Vegas to play the Raiders.

NFL Week 5 Odds

For the complete list of NFL Week 5 odds, refer to the information below.

MatchupDateTimeSpreadOver/Under
Bears vs. CommandersThursday, October 0508:15 PM ETCommanders -6.5 (-110)44.5
Jaguars vs. Bills (London)Sunday, October 809:30 AM ETBills -5.5 (-110)48.5
Titans vs. ColtsSunday, October 801:00 PM ETColts PK (-110)42.5
Texans vs. FalconsSunday, October 801:00 PM ETFalcons -2 (-110)41.5
Panthers vs. LionsSunday, October 801:00 PM ETLions -9 (-110)45
Ravens vs. SteelersSunday, October 801:00 PM ETRavens -3.5 (-110)38
Saints vs. PatriotsSunday, October 801:00 PM ETPatriots -1.5 (-110)40
Giants vs. DolphinsSunday, October 801:00 PM ETDolphins -11 (-110)50
Eagles vs. RamsSunday, October 801:00 PM ETEagles -4 (-110)50.5
Bengals vs. CardinalsSunday, October 804:05 PM ETBengals -3 (-110)44.5
Jets vs. BroncosSunday, October 804:25 PM ETBroncos – (-110)43.5
Chiefs vs. VikingsSunday, October 804:25 PM ETChiefs -5 (-110)53
Cowboys vs. 49ersSunday, October 808:20 PM ET49ers -4 (-110)45
Packers vs. RaidersMonday, October 908:15 PM ETPackers -2 (-110)44.5

*Odds via Caesars Sportsbook (check our Caesars Sportsbook Review) as of October 4, 2023.


Best NFL Week 5 Spread Available

MatchupCurrent Best Spread Available
Bears vs. CommandersCommanders -6.5 (-110) at Caesars Sportsbook
Jaguars vs. Bills (London)Bills -5.5 (-110) at Caesars Sportsbook
Titans vs. ColtsColts PK (-110) at Caesars Sportsbook
Texans vs. FalconsFalcons -2 (-109) at SugarHouse
Panthers vs. LionsLions -9 (-110) at Caesars Sportsbook
Ravens vs. SteelersRavens -3.5 (-110) at Caesars Sportsbook
Saints vs. PatriotsPatriots -1.5 (-110) at Caesars Sportsbook
Giants vs. DolphinsDolphins -11 (-110) at SBK
Eagles vs. RamsEagles -4 (-110) at Caesars Sportsbook
Bengals vs. CardinalsBengals -3 (-110) (-110) at Caesars Sportsbook
Jets vs. BroncosBroncos -1.5 (-110) at SugarHouse
Chiefs vs. VikingsChiefs -5 (-110) at Caesars Sportsbook
Cowboys vs. 49ers49ers -3.5 (-108) at BetRivers
Packers vs. RaidersPackers -1.5 (-112) at SBK

More Weekly NFL Odds Previews

Eager to explore the upcoming NFL schedule for the most recent odds or curious about the odds of a game that has already taken place? Check out our odds preview covering all 18 weeks of the NFL regular season!

*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.

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