The NFL Week 3 schedule is very promising. As all 32 teams will be in action, with the historic rivalry between Aaron Rodgers and Tom Brady having a new chapter on Sunday. Below you can check out the latest odds for all Week 3 clashes.
The Packers visit the Buccaneers in what is expected to be the game of the week. Other can’t-miss contests include the Bills visiting the Dolphins in a key AFC East battle and the 49ers clashing with a familiar face in Russell Wilson, who is now under center for the Broncos.
Here is the full slate of games and the latest NFL Week 3 odds.
NFL Week 3 Odds
These are the NFL odds for Week 3, headlined by the Sunday afternoon game between the Green Bay Packers and Tampa Bay Buccaneers in what could be a playoff preview.
| Matchup | Time | Spread | Over/Under |
|---|---|---|---|
| Steelers vs. Browns | Thursday, September 22, 2022 – 08:15 PM EST at FirstEnergy Stadium | Browns -3.5 | N/A |
| Saints vs. Panthers | Sunday, September 25, 2022 – 01:00 PM EST at Bank of America Stadium | Saints -1.5 | N/A |
| Texans vs. Bears | Sunday, September 25, 2022 – 01:00 PM EST at Soldier Field | Bears -3.5 | N/A |
| Chiefs vs. Colts | Sunday, September 25, 2022 – 01:00 PM EST at Lucas Oil Stadium | Chiefs -2.5 | N/A |
| Bills vs. Dolphins | Sunday, September 25, 2022 – 01:00 PM EST at Hard Rock Stadium | Bills -4 | N/A |
| Lions vs. Vikings | Sunday, September 25, 2022 – 01:00 PM EST at U.S. Bank Stadium | Vikings -6.5 | N/A |
| Ravens vs. Patriots | Sunday, September 25, 2022 – 01:00 PM EST at Gillette Stadium | Patriots PK | N/A |
| Bengals vs. Jets | Sunday, September 25, 2022 – 01:00 PM EST at MetLife Stadium | Bengals -4.5 | N/A |
| Raiders vs. Titans | Sunday, September 25, 2022 – 01:00 PM EST at Nissan Stadium | Titans -2.5 | N/A |
| Eagles vs. Commanders | Sunday, September 25, 2022 – 01:00 PM EST at FedExField | Eagles -2.5 | N/A |
| Jaguars vs. Chargers | Sunday, September 25, 2022 – 04:05 PM EST at SoFi Stadium | Chargers -10 | N/A |
| Rams vs. Cardinals | Sunday, September 25, 2022 – 04:25 PM EST at State Farm Stadium | Rams -1 | N/A |
| Falcons vs. Seahawks | Sunday, September 25, 2022 – 04:25 PM EST at Lumen Field | Seahawks -3.5 | N/A |
| Packers vs. Buccaneers | Sunday, September 25, 2022 – 04:25 PM EST at Raymond James Stadium | Buccaneers -3 | 52 |
| 49ers vs. Broncos | Sunday, September 25, 2022 – 08:20 PM EST at Empower Field at Mile High | Broncos -3 | 46.5 |
| Cowboys vs. Giants | Monday, September 26, 2022 – 08:15 PM EST at MetLife Stadium | Cowboys -3 | 48 |
| Matchup | Best Spread Available |
|---|---|
| Steelers vs. Browns | Browns -3.5 at Caesars Sportsbook |
| Saints vs. Panthers | Saints -1 at DraftKings |
| Texans vs. Bears | Bears -3 at DraftKings |
| Chiefs vs. Colts | Chiefs -2.5 at Caesars Sportsbook |
| Bills vs. Dolphins | Bills -3.5 at DraftKings |
| Lions vs. Vikings | Vikings -6.5 at Caesars Sportsbook |
| Ravens vs. Patriots | Patriots PK at Caesars Sportsbook |
| Bengals vs. Jets | Bengals -4.5 at Caesars Sportsbook |
| Raiders vs. Titans | Titans -1 at DraftKings |
| Eagles vs. Commanders | Eagles PK at DraftKings |
| Jaguars vs. Chargers | Chargers -10 at DraftKings |
| Rams vs. Cardinals | Rams -1 at Caesars Sportsbook |
| Falcons vs. Seahawks | Seahawks -3.5 at Caesars Sportsbook |
| Packers vs. Buccaneers | Buccaneers -3 at Caesars Sportsbook |
| 49ers vs. Broncos | Broncos -2.5 at DraftKings |
| Cowboys vs. Giants | Cowboys -3 at Caesars Sportsbook |
