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The upcoming MLB matchup on February 21, 2026, features the Colorado Rockies visiting the Arizona Diamondbacks at Salt River Fields at Talking Stick in Scottsdale, AZ. This exciting game will be broadcasted on the arid TV station, offering fans a great viewing experience. Our expert picks and betting tips highlight the importance of analyzing pitcher handedness and hitters' performance against right or left-handed starters to inform smart betting decisions.
In this game, the starting pitchers' handedness will be crucial. If the Diamondbacks start a right-handed pitcher, bettors should consider how the Rockies' hitters perform against righties, and vice versa. This matchup's prediction leans towards the Arizona Diamondbacks winning with a close score of 4-3, favoring the moneyline market. Our prediction model has been profitable in recent games, boasting a hit rate of over 55% on moneyline bets, making this a high EV opportunity for bettors.
For more detailed analysis and additional picks, visit our MLB picks and predictions page. Don't miss out on the best betting odds available today for both teams at SugarHouse to maximize your potential returns. Place your bets confidently and enjoy the thrilling MLB action between the Colorado Rockies and Arizona Diamondbacks on February 21, 2026.
BALD. Kremer (R) 100% -140BetOnline | |||||||
NYYUndecided - -157BetOnline | |||||||
TBUndecided - -130BetOnline | |||||||
![]() MINJ. Ryan (R) - -103Bovada | |||||||
![]() TORE. Lauer (L) 0% -118Bookmaker | |||||||
NYMB. Waddell (L) - -145BetOnline | |||||||
KCR. Bergert (R) - -118Bookmaker | |||||||
![]() CHCM. Boyd (L) - -130BetOnline | |||||||
![]() CWSC. Murphy (L) - -110BetOnline | |||||||
![]() AZM. Bratt (L) - -160BetOnline | |||||||
LAAJ. Soriano (R) - +135BetOnline | |||||||
SEAE. Hancock (R) - -135BetOnline |