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Feb 21, 2026 3:05 PM EST
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Athletics vs Chicago White Sox Picks for MLB 2026
Updated:Feb 21, 2026 1:12 AM EST
The upcoming MLB matchup on February 21, 2026, features the Athletics vs Chicago White Sox at Camelback Ranch in Phoenix, AZ. This early season game is scheduled to start at 3:05 PM local time and will be broadcast on chsn, making it accessible for fans and bettors alike. Our picks for this game draw on detailed analysis of both teams' recent performances and pitching matchups to provide you with valuable betting tips.
The Athletics will face the White Sox in a game where pitching will play a crucial role. If the starting pitcher is right-handed, hitters' performance against right-handed pitchers will be a key factor, and vice versa for left-handed starters. This insight can help you make smarter bets by anticipating offensive production based on pitcher-batter matchups.
Our prediction model, which has been profitable over the last 10 games with a strong hit rate and positive EV in point spread markets, favors the Chicago White Sox to win with a predicted score of 5-3. The best bet is on the White Sox moneyline, as our analysis shows their edge at home at Camelback Ranch in Phoenix.
For more detailed MLB picks and insights, check out our comprehensive MLB picks and predictions. Ready to place your bets? Find the top odds today at SugarHouse and get in on the action with confidence. Don't miss this exciting start to the 2026 MLB season with expert picks guiding your wagers.
MLB
Money
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- 1st 5
MLBSat 02/21
 BALD. Kremer (R) 100% -140BetOnline | |||||||
 NYYUndecided - -157BetOnline | |||||||
 TBUndecided - -130BetOnline | |||||||
 MINJ. Ryan (R) - -103Bovada | |||||||
 TORE. Lauer (L) 0% -118Bookmaker | |||||||
 NYMB. Waddell (L) - -145BetOnline | |||||||
 KCR. Bergert (R) - -118Bookmaker | |||||||
 CHCM. Boyd (L) - -130BetOnline | |||||||
 CWSC. Murphy (L) - -110BetOnline | |||||||
 AZM. Bratt (L) - -160BetOnline | |||||||
 LAAJ. Soriano (R) - +135BetOnline | |||||||
 SEAE. Hancock (R) - -135BetOnline |
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