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Boston Red Sox vs Minnesota Twins Picks
Updated:Feb 21, 2026 1:13 AM EST
The upcoming MLB matchup on February 21, 2026, features the Boston Red Sox visiting the Minnesota Twins at Lee Health Sports Complex in Fort Myers, FL. This exciting game is part of the 2026 MLB season and will be broadcasted live on NESN, giving baseball enthusiasts a great viewing experience.
For bettors, this Boston Red Sox vs Minnesota Twins game offers intriguing opportunities. The Twins, playing at home, will look to leverage their familiarity with Lee Health Sports Complex. Analyzing the starting pitchers' handedness and hitters' performance against right or left-handed pitching can provide valuable insights for your picks and betting tips. Our model suggests a competitive matchup, with a predicted score favoring the Boston Red Sox 5-4 on the moneyline, indicating a close game that could go either way.
Our prediction model has been profitable over the last 10 games, boasting a strong hit rate of 60% on moneyline bets, highlighting the value in these markets. The under 8.5 total runs market also shows a high expected value (EV) and cover percentage, making it a smart play for bettors looking for reliable parlays. These insights can help you make smart betting decisions and maximize your returns.
Don't miss out on expert picks for this game and the entire MLB season. Check out our comprehensive MLB picks and predictions for the best betting advice and odds. For the best odds available today on the Boston Red Sox and Minnesota Twins, explore top sportsbooks like SugarHouse to place your bets confidently.
MLB
Money
Game
- Game
- 1st 5
MLBSat 02/21
 BALD. Kremer (R) 100% -140BetOnline | |||||||
 NYYUndecided - -157BetOnline | |||||||
 TBUndecided - -130BetOnline | |||||||
 MINJ. Ryan (R) - -103Bovada | |||||||
 TORE. Lauer (L) 0% -118Bookmaker | |||||||
 NYMB. Waddell (L) - -145BetOnline | |||||||
 KCR. Bergert (R) - -118Bookmaker | |||||||
 CHCM. Boyd (L) - -130BetOnline | |||||||
 CWSC. Murphy (L) - -110BetOnline | |||||||
 AZM. Bratt (L) - -160BetOnline | |||||||
 LAAJ. Soriano (R) - +135BetOnline | |||||||
 SEAE. Hancock (R) - -135BetOnline |
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