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The Major League Baseball matchup between the Pittsburgh Pirates and Chicago Cubs is scheduled for April 12, 2026, at Wrigley Field in Chicago, IL. Broadcasted on Marquee Sports Network, this game features a predicted score favoring the Cubs 5-3 with a point spread of Cubs -1.5. Our picks and betting tips highlight the Cubs' advantage against right-handed pitching, supported by a 51.5% probability to cover the spread. The under 12.5 total is also favored given the 86.7% hit rate in similar markets. For detailed league insights, visit our MLB picks page.
PHIA. Painter (R) 7-733% -136Bet105 | |||||||
BALC. Povich (L) 7-7100% -123BetOnline | |||||||
![]() TORM. Scherzer (R) 6-80% -116MyBookie | |||||||
TBD. Rasmussen (R) 7-775% +140BetOnline | |||||||
![]() DETT. Skubal (L) 6-9100% -193BetOnline | |||||||
NYMF. Peralta (R) 7-837% -160BetOnline | |||||||
CINA. Abbott (L) 9-6- -102Bet105 | |||||||
MILB. Woodruff (R) 8-60% -190Everygame | |||||||
KCN. Cameron (L) 7-80% -175BetOnline | |||||||
STLA. Pallante (R) 8-6100% +115Everygame | |||||||
![]() CHCJ. Taillon (R) 6-829% -127BetOnline | |||||||
![]() SDN. Pivetta (R) 9-60% -223Bet105 | |||||||
SEAL. Gilbert (R) 6-9- -150BetOnline | |||||||
LADR. Sasaki (R) 11-333% -122Bet105 | |||||||
ATLC. Sale (L) 9-60% -184BetAnything |