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The upcoming MLB game between the Houston Astros and Seattle Mariners is scheduled for April 13, 2026, at 4:10 PM ET at T-Mobile Park in Seattle, WA. The game will be broadcast on Seam. Our picks favor the Houston Astros with a predicted score of 4.34 to 3.62 in favor of Seattle, but Houston is expected to cover the +1.5 spread with a 58.4% probability. The total score is predicted just below 8 runs, suggesting a lean towards under 7.5. Seattle's hitters perform moderately against right-handed pitching, while Houston's offense shows resilience, influencing our betting tips. Our model has a solid track record, with profitable outcomes in point spread markets over the last 10 games, demonstrating a 58.4% hit rate and positive EV. For more detailed analysis, visit our MLB picks page.
SEAG. Kirby (R) 7-940% -164BetAnything | |||||||
BALT. Rogers (L) 8-70% -126BetOnline | |||||||
PHIC. Sánchez (L) 7-850% -180BetOnline | |||||||
PITP. Skenes (R) 9-633% -210BetOnline | |||||||
NYYW. Warren (R) 8-710% -174BetAnything | |||||||
ATLG. Holmes (R) 10-612% -136BetAnything | |||||||
![]() MINB. Ober (R) 9-750% +150Bookmaker | |||||||
STLM. Liberatore (L) 8-775% +106Bookmaker | |||||||
![]() ATHL. Severino (R) 8-733% +120Everygame | |||||||
LADJ. Wrobleski (L) 11-417% -163BetAnything |