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The upcoming MLB game between Houston Astros and Seattle Mariners is scheduled for April 11, 2026, at T-Mobile Park in Seattle, WA. Broadcasted on SEAM, this matchup features Seattle as the home team with a retractable dome venue. Our picks and betting tips indicate a predicted score of Seattle 4.04 to Houston 3.54, favoring Houston +1.5 on the point spread with a 61.0% probability to cover. The predicted total score is approximately 7.57, with an edge towards the under 7.5 market showing a 54.4% hit rate and positive EV. Notably, Houston's hitters perform well against right-handed pitchers, aligning with the probable starting pitcher profile, which supports our betting tips. Our prediction model has been profitable in recent games, particularly in point spread markets, enhancing confidence for this event. For more detailed analysis, visit our MLB picks and predictions.
PHIT. Walker (R) 6-775% -130BetAnything | |||||||
![]() DETC. Mize (R) 5-9- -138BetOnline | |||||||
![]() CHCE. Cabrera (R) 6-70% -142Bet105 | |||||||
![]() TORE. Lauer (L) 6-7- -106Everygame | |||||||
KCM. Wacha (R) 6-8100% -183BetOnline | |||||||
CINB. Williamson (L) 8-6- -132BetOnline | |||||||
NYMK. Senga (R) 7-7- -153Bet105 | |||||||
TBN. Martinez (R) 6-70% +174Bookmaker | |||||||
MILK. Harrison (L) 8-5- -170BetAnything | |||||||
BALC. Bassitt (R) 6-7- +105Everygame | |||||||
ATLM. Pérez (L) 9-5100% -110BetOnline | |||||||
STLK. Leahy (R) 8-5100% +128Everygame | |||||||
![]() SDG. Márquez (R) 8-650% -157BetOnline | |||||||
LADE. Sheehan (R) 10-350% -175Everygame | |||||||
SEAL. Castillo (R) 5-90% -140BetAnything |