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San Diego Padres vs Kansas City Royals Picks
Updated:Feb 21, 2026 1:09 AM EST
Get ready for the exciting MLB matchup on February 21, 2026, as the San Diego Padres take on the Kansas City Royals at Surprise Stadium in Surprise, AZ. This game offers an excellent opportunity for bettors looking to leverage detailed analysis and expert picks. The Padres and Royals will clash in what promises to be an engaging baseball contest broadcasted on local TV stations.
Our picks for this game are backed by in-depth analysis, including the impact of the starting pitchers on both teams. Understanding how hitters perform against right-handed versus left-handed pitchers can significantly influence betting decisions. For this matchup, the starting pitchers' handedness will be a crucial factor to watch.
Historically, our prediction model has been profitable over the last 10 games, boasting a solid hit rate and positive expected value (EV) in similar MLB contests. Our betting tips suggest a predicted score of Kansas City Royals 5, San Diego Padres 3, with the Royals favored on the moneyline. This aligns with our data-driven insights and the current form of both teams.
For bettors seeking more comprehensive MLB picks and predictions, explore our detailed league analysis at Expert MLB Picks and Predictions. Plus, discover the best sportsbooks for placing your bets safely and securely, like SugarHouse.
Don't miss out on this thrilling MLB game and make informed betting choices with our expert picks and betting tips for San Diego Padres vs Kansas City Royals at Surprise Stadium on February 21, 2026.
MLB
Money
Game
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- 1st 5
MLBSat 02/21
 BALD. Kremer (R) 100% -140BetOnline | |||||||
 NYYUndecided - -157BetOnline | |||||||
 TBUndecided - -130BetOnline | |||||||
 MINJ. Ryan (R) - -103Bovada | |||||||
 TORE. Lauer (L) 0% -118Bookmaker | |||||||
 NYMB. Waddell (L) - -145BetOnline | |||||||
 KCR. Bergert (R) - -118Bookmaker | |||||||
 CHCM. Boyd (L) - -130BetOnline | |||||||
 CWSC. Murphy (L) - -110BetOnline | |||||||
 AZM. Bratt (L) - -160BetOnline | |||||||
 LAAJ. Soriano (R) - +135BetOnline | |||||||
 SEAE. Hancock (R) - -135BetOnline |
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