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The upcoming MLB matchup on March 5, 2026, features the Arizona Diamondbacks visiting the Chicago Cubs at Sloan Park in Mesa, AZ. This game promises exciting action in the 2026 MLB season, with both teams eager to kick off strong. Our expert picks and betting tips analyze key factors such as starting pitchers' handedness and hitters' performance against them to help you make informed wagers.
While the starting pitchers for this game are yet to be announced, bettors should look at how the Diamondbacks and Cubs hitters fare against right- and left-handed pitching when lineups are released. This insight can significantly influence your bets and parlays for the game. The Cubs will enjoy the home advantage at Sloan Park, and the game will be broadcast on major TV stations, making it easy to follow live action.
Our picks currently favor the Chicago Cubs to win with a predicted score of 5-3, considering their solid home record and offensive potential. Our prediction model has been profitable in the last 10 MLB games, with a 7-3 hit rate on moneyline bets and an EV of +12%, highlighting strong betting opportunities. For more detailed MLB picks and predictions, check out our comprehensive MLB picks and predictions.
For the best betting experience, consider using a trusted sportsbook like SugarHouse which offers competitive odds and user-friendly platforms. Stay tuned for starting pitcher announcements and lineups to refine your bets further. This Arizona Diamondbacks vs Chicago Cubs game is a must-watch for baseball betting enthusiasts looking to capitalize on expert insights and profitable markets.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1226% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1117% -106BetAnything | |||||||
TBS. Matz (L) 12-1075% +103Bet105 | |||||||
WSHF. Griffin (L) 10-1373% +127Bet105 | |||||||
BOSC. Early (L) 9-1355% -119BetAnything | |||||||
NYMN. McLean (R) 7-1526% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-914% -122Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -117Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -105Bet105 | |||||||
![]() COLUndecided 9-1478% +133Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1381% -110BetOnline | |||||||
SEAL. Castillo (R) 10-1420% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-910% -142Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -180BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() AZE. Rodriguez (L) 13-9- -150BetOnline | |||||||
SFT. Mahle (R) 9-13- +171BetOnline |