- Run Line
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- Merged
The upcoming MLB matchup between the Chicago White Sox and Arizona Diamondbacks is scheduled for April 22, 2026, at Chase Field in Phoenix, AZ. The game will be broadcast on arid TV station. Current odds favor the Diamondbacks with a Moneyline of -145, showing a slight shift from opening lines where the White Sox were underdogs at +131. The run line is set at -1.5 -110 for Arizona and +1.5 -110 for Chicago, indicating a competitive betting market. Totals are listed at 9 runs with the Over at -127. These betting lines highlight market confidence in the Diamondbacks' home advantage and pitching staff. For detailed betting odds, visit the MLB odds page.
TBC. Legumina (R) 44-3342% -136BetAnything | |||||||
PITB. Chandler (R) 40-4067% +135Everygame | |||||||
SFL. Roupp (R) 33-4658% -120Bookmaker | |||||||
![]() DETT. Melton (R) 34-4665% -107Bookmaker | |||||||
WSHC. Cavalli (R) 41-4067% +155Everygame | |||||||
![]() TORK. Gausman (R) 39-4117% -126Heritage | |||||||
NYMF. Peralta (R) 34-4620% -102Bookmaker | |||||||
BOSC. Early (L) 32-4666% +133Everygame | |||||||
STLM. McGreevy (R) 42-3611% -129BetOnline |