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The upcoming MLB game on April 25, 2026, features the San Diego Padres visiting the Arizona Diamondbacks at Estadio Alfredo Harp Helu in Mexico City. This regular season matchup is set for 6:05 PM ET and will be broadcast on arid TV. Current odds favor the Diamondbacks with a run line of -1.5 +145, compared to the Padres at +1.5 -165, showing a shift from opening odds that indicates increased confidence in Arizona's chances. The total runs are set at 15.5 with an over priced at -122, reflecting expectations of a high-scoring game. Bettors can explore detailed betting lines for this MLB event and review sportsbook options to make informed wagers.
TBC. Legumina (R) 44-3343% -132Bet105 | |||||||
PITB. Chandler (R) 40-4073% +135Everygame | |||||||
SFL. Roupp (R) 33-4655% -122Bookmaker | |||||||
![]() DETT. Melton (R) 34-4670% -108BetAnything | |||||||
WSHC. Cavalli (R) 41-4071% +170Bookmaker | |||||||
![]() TORK. Gausman (R) 39-4121% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4616% -105Bet105 | |||||||
BOSC. Early (L) 32-4672% +145Everygame | |||||||
STLM. McGreevy (R) 42-3613% -129BetOnline |