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Before the game on September 19, 2025, the New York Yankees will face off against the Baltimore Orioles at Oriole Park at Camden Yards in Baltimore, MD. This MLB regular season clash promises to be a thrilling encounter as the Yankees, having a strong record, aim to extend their dominance over the Orioles. The Yankees' hitters have shown exceptional performance against right-handed pitchers, which could be pivotal in this matchup. On the other hand, the Orioles will rely on their home advantage and recent improvements in pitching to challenge the Yankees. Our prediction model gives the Yankees a 59.7% chance to win, with a predicted score of 4.79 to 3.87. The best bet for this game is the Yankees' moneyline, considering their recent form and higher EV. Additionally, the under 9 total runs market offers a promising opportunity with a 57.5% hit rate. For more insights and predictions, check our MLB picks page. Catch the game on MASN and make sure to Start your OddsTrader Turbo subscription for smarter betting strategies.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1230% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +130BetAnything | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1525% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +130Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-913% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |