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The Cleveland Guardians head to Boston for a thrilling MLB showdown against the Boston Red Sox on September 3, 2025. This game at Fenway Park in Boston, MA, promises an exciting clash as the Guardians aim to bounce back from their recent loss to the Red Sox. With Boston's righthanded starting pitcher, the Guardians' hitters need to step up their game, having struggled against righties this season. Meanwhile, the Red Sox, riding high after their recent win, are ready to leverage their home advantage. Our prediction model, which has been profitable in 6 of the last 10 games, favors Boston with a predicted score of 6-4. The best bet for this game is Boston -1.5, with a 57.2% probability of covering the spread. Catch the game live on NESN and make sure to check out our MLB picks page for more insights. Ready to bet smarter? Start your OddsTrader Turbo subscription today and gain the edge you need.
![]() CLEP. Messick (L) 13-1120% -147Bookmaker | |||||||
MIAC. Paddack (R) 11-1226% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1119% -106BetAnything | |||||||
TBS. Matz (L) 12-1072% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bet105 | |||||||
BOSC. Early (L) 9-1351% -121Bet105 | |||||||
NYMN. McLean (R) 7-1522% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-915% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1479% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1379% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1425% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-912% -142Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |