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The upcoming MLB matchup on May 1, 2026, features the Houston Astros visiting the Boston Red Sox at Fenway Park in Boston, MA. Broadcast on NESN, the game predicts a close contest with Houston favored to cover the +1.5 spread, holding a 61.6% probability and an EV of -5.2%. Boston's predicted score is 4.74, slightly edging Houston's 4.41. Notably, Houston's hitters have shown resilience against right-handed pitchers, which may influence bets. Our picks and betting tips favor Houston on the spread, supported by a profitable recent record in point spread markets. For comprehensive MLB picks, see MLB picks and predictions.
PHIA. Nola (R) 30-2973% -142Bovada | |||||||
TBS. Matz (L) 36-2115% -135BetOnline | |||||||
WSHM. Mikolas (R) 31-3055% -110Heritage | |||||||
BOSC. Early (L) 25-330% -131Bet105 | |||||||
NYYC. Schlittler (R) 36-2320% -236Bet105 | |||||||
CINA. Abbott (L) 30-2917% -118BetOnline | |||||||
ATLB. Elder (R) 40-2021% -112Bet105 | |||||||
MILK. Harrison (L) 36-2115% -150Bookmaker | |||||||
![]() MINC. Prielipp (L) 28-3386% +111Heritage | |||||||
STLD. May (R) 31-2792% +104Bookmaker | |||||||
![]() CHCJ. Taillon (R) 32-2833% -120BetOnline | |||||||
HOUM. Burrows (R) 27-3425% -106Bet105 | |||||||
LAAG. Rodriguez (R) 23-3850% -155Bovada | |||||||
![]() AZM. Soroka (R) 32-2717% +141Bookmaker | |||||||
SEAL. Gilbert (R) 32-2910% -127Bookmaker | |||||||
WSHA. Alvarez (L) 31-30- -115Bookmaker | |||||||
TBN. Martinez (R) 36-21- -138Bookmaker | |||||||
![]() MINT. Bradley (R) 28-33- +106Bookmaker | |||||||
SEAG. Kirby (R) 32-29- -153Bookmaker | |||||||
PHIC. Sánchez (L) 30-29- -144Bookmaker | |||||||
BOSP. Tolle (L) 25-33- -130Bookmaker | |||||||
NYYG. Cole (R) 36-23- -233Bookmaker | |||||||
CINC. Paddack (R) 30-29- -120Bookmaker | |||||||
ATLG. Holmes (R) 40-20- -120Bookmaker | |||||||
MILUndecided 36-21- -257Bookmaker | |||||||
STLA. Pallante (R) 31-27- -102Bookmaker | |||||||
![]() CHCC. Rea (R) 32-28- -129Bookmaker | |||||||
HOUS. Arrighetti (R) 27-34- -108Bookmaker | |||||||
LAAW. Ureña (R) 23-38- -163Bookmaker | |||||||
![]() AZZ. Gallen (R) 32-27- +102Bookmaker |