- Run Line
- Money
- Total
- Merged
The upcoming MLB matchup on May 22, 2026, features the Minnesota Twins visiting the Boston Red Sox at Fenway Park in Boston, MA. Broadcasted on NESN, this game offers detailed betting odds analysis. The Red Sox are favored on the moneyline at -145, with the Twins at +131. The run line shows Boston at -1.5 -110 and Minnesota at +1.5 -172. Notably, the opening run line was -1.5 -110, indicating increased confidence in the Red Sox. Totals are set at 7.5 with equal odds on over and under. These betting lines provide valuable insights for bettors evaluating game dynamics. For more detailed MLB betting odds, see MLB odds page.
![]() TORS. Bieber (R) 39-3972% -124Everygame | |||||||
![]() DETC. Mize (R) 34-4445% +102Bet105 | |||||||
TBS. McClanahan (L) 43-3217% -177BetOnline | |||||||
PITM. Keller (R) 39-390% +113BetOnline | |||||||
MIAS. Alcantara (R) 40-3915% -152BetOnline | |||||||
WSHZ. Littell (R) 41-3879% +155Everygame | |||||||
CINN. Lodolo (L) 37-4039% -105BetAnything | |||||||
NYMK. Senga (R) 34-4384% -111Bookmaker | |||||||
![]() CWSS. Burke (R) 40-3735% +102Everygame | |||||||
![]() MINK. Rojas (L) 38-4281% +157Everygame | |||||||
STLK. Leahy (R) 42-3446% -108BetOnline | |||||||
![]() COLS. Sullivan (L) 31-4879% +145BetOnline | |||||||
LAAR. Johnson (R) 32-4850% +128Everygame | |||||||
![]() SDG. Canning (R) 40-3750% +101Everygame | |||||||
SFR. Ray (L) 31-4665% -135Bookmaker | |||||||
NYMUndecided 34-43- - |