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As the Boston Red Sox prepare to face the New York Yankees on September 30, 2025, anticipation is building for this Major League Baseball showdown at Yankee Stadium in Bronx, NY. The Red Sox have been impressive, especially against righthanded pitchers, which could pose a challenge for the Yankees, who have struggled against teams with strong righty hitters. Our picks suggest Boston has a slight edge, with a predicted score of 3-1 in favor of the Red Sox. This match will be broadcasted on ESPN networks, making it a must-watch for baseball fans and bettors alike. With Boston's recent success, including a win over the Yankees in their last matchup, bettors might consider Boston +1.5 for a high EV bet. Our prediction model has been profitable in point spreads, with a hit rate of 52.4% over the last ten games. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more insights, check out our MLB picks page.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1226% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1117% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103Bet105 | |||||||
WSHF. Griffin (L) 10-1375% +127Bet105 | |||||||
BOSC. Early (L) 9-1353% -119BetAnything | |||||||
NYMN. McLean (R) 7-1524% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-914% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1140% -105Bet105 | |||||||
![]() COLJ. Herget (R) 9-1481% +133Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1427% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-910% -142Bet105 | |||||||
SFL. Roupp (R) 9-1392% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() AZE. Rodriguez (L) 13-9- -150BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |