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The upcoming MLB game between the San Diego Padres and Boston Red Sox is set for April 5, 2026, at Fenway Park in Boston, MA, broadcast on NESN. Our picks indicate Boston has a 68.4% probability to win with a predicted score of approximately 5.8 to San Diego's 3.8. Boston's hitters perform well against right-handed pitchers, which is advantageous given the expected pitching matchup. Our predictions have been profitable in recent games, with a 54.3% hit rate on Boston covering the +1.5 spread, suggesting a favorable betting tip. Explore more detailed MLB picks and insights at MLB picks and predictions.
TBC. Legumina (R) 44-3344% -135Bet105 | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4659% -123Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -108BetAnything | |||||||
WSHC. Cavalli (R) 41-4070% +163Bookmaker | |||||||
![]() TORK. Gausman (R) 39-4119% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4670% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |