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The Chicago Cubs face the Chicago White Sox on May 17, 2026, at Rate Field in Chicago, IL, in an MLB matchup broadcasted on chsn. Our picks predict the Cubs to win with a score of approximately 5 to 3. The Cubs' hitters have a 65.6% success rate against right-handed pitchers, while the White Sox's rate is lower at 34.4%, influencing our betting tips favoring the Cubs on the moneyline and spread. Our model has shown a 61.8% hit rate on under 8.5 total runs, indicating a strong edge for the under bet. For more detailed MLB picks, visit MLB picks and predictions.
TBC. Legumina (R) 44-3342% -136BetAnything | |||||||
PITB. Chandler (R) 40-4067% +135Everygame | |||||||
SFL. Roupp (R) 33-4658% -117Bookmaker | |||||||
![]() DETT. Melton (R) 34-4665% -104Bookmaker | |||||||
WSHC. Cavalli (R) 41-4067% +155Everygame | |||||||
![]() TORK. Gausman (R) 39-4117% -126Heritage | |||||||
NYMF. Peralta (R) 34-4620% -102Bookmaker | |||||||
BOSC. Early (L) 32-4666% +141BetAnything | |||||||
STLM. McGreevy (R) 42-3611% -129BetOnline |