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The upcoming MLB game on May 23, 2026, features the Houston Astros visiting the Chicago Cubs at Wrigley Field in Chicago, IL. Broadcasted on Marquee Sports Network, this matchup offers insightful betting tips with the Cubs predicted to edge out a 4-3 victory. The starting pitcher for Chicago is right-handed, favoring Houston hitters who perform moderately well against right-handed pitching. Our picks lean towards Houston covering the +1.5 spread, with a 56.6% probability. For detailed MLB picks, visit MLB picks and predictions.
MIAE. Pérez (R) 41-3969% +118Everygame | |||||||
![]() CWSE. Fedde (R) 41-3740% +108Everygame | |||||||
![]() COLK. Freeland (L) 31-49100% +155Everygame | |||||||
LAAJ. Soriano (R) 33-4837% -119Bet105 | |||||||
TBG. Jax (R) 43-3314% -144Bookmaker | |||||||
![]() DETT. Skubal (L) 34-4521% -137BetOnline | |||||||
PITB. Ashcraft (R) 39-4033% -111BetOnline | |||||||
WSHM. Mikolas (R) 41-3967% +122Everygame | |||||||
![]() TORT. Yesavage (R) 39-4011% -150BetOnline | |||||||
CINR. Lowder (R) 37-4190% +130Everygame | |||||||
NYMS. Manaea (L) 34-44- +106Bookmaker | |||||||
![]() MINJ. Ryan (R) 38-4392% +157Everygame | |||||||
STLM. Liberatore (L) 42-35- -110Everygame | |||||||
![]() SDJ. Sears (L) 41-3786% +122Bookmaker | |||||||
SFT. Mahle (R) 32-4687% +115Everygame |