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As the Chicago Cubs gear up to face the Pittsburgh Pirates on September 17, 2025, at PNC Park in Pittsburgh, PA, MLB fans and bettors alike are eagerly anticipating this matchup. This regular season game promises to be a thrilling encounter as the Cubs aim to maintain their dominance. The Cubs, who recently secured a 4-1 victory over the Pirates, are the favorites with a moneyline of -165 at Caesars, while the Pirates stand at +140. The run line is set at -1.5 -110 for the Cubs and +1.5 -110 for the Pirates, indicating a closely contested game.
For those interested in the over under, the line is set at 8.0 with both over and under priced at -110. This provides an interesting angle for bettors looking to capitalize on the game’s potential scoring dynamics. Broadcasting live on MLB Network and Marquee, this game is a must-watch for baseball enthusiasts and bettors aiming to make informed decisions.
Understanding the odds and betting lines is crucial for making smart wagers. With the current odds reflecting the Cubs as favorites, bettors should consider the recent form and head-to-head statistics. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more detailed betting odds and insights, check out our MLB odds page.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1230% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +130BetAnything | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1525% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +130Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-913% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |