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Before the much-anticipated MLB clash on October 1, 2025, between the San Diego Padres and Chicago Cubs at Wrigley Field in Chicago, Illinois, fans are buzzing with excitement. This Game 2 showdown is crucial as the Cubs lead the series 1-0. The Padres aim to bounce back after their loss in Game 1. Our picks favor the Cubs, with a predicted score of Cubs 5.2 to Padres 3.7. The Cubs have a 65.1% chance of winning, making them a strong bet for today's game. Additionally, consider betting on the 'Over 6.5' total points as our model predicts a total score of 8.9. Tune in to ABC or ESPN networks for live coverage. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Our prediction model has been profitable in the last 10 games, especially in the American Total market, hitting 6 wins. Explore more MLB picks and predictions for insightful betting tips.
![]() CLEP. Messick (L) 13-1118% -144Bookmaker | |||||||
MIAC. Paddack (R) 11-1224% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1119% -106BetAnything | |||||||
TBS. Matz (L) 12-1070% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1346% -121Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-915% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -118Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1480% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1378% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1423% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |