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The much-anticipated MLB clash between the Tampa Bay Rays and the Chicago Cubs is set to take place on September 12, 2025, at the historic Wrigley Field in Chicago, IL. This game promises to deliver high-octane action, with the Cubs holding a slight edge in the predictions. Historically, the Cubs have performed well against right-handed pitchers, which could be a decisive factor in this matchup. According to our model, the Cubs are predicted to win with a score of 4.39-3.46, making them a strong pick for bettors. Our previous predictions have shown a hit rate of over 60% in similar matchups, and we anticipate a profitable outcome for those betting on the Cubs' moneyline. Tune in to fdssun for live coverage and explore more MLB insights on our MLB picks page. Ready to make smarter bets? Start your OddsTrader Turbo subscription now and capitalize on our expert analysis.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1229% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1073% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +137Bovada | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1524% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -127BetOnline | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1479% +130Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1381% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-912% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |