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As we gear up for the MLB showdown on September 14, 2025, the Tampa Bay Rays are set to face off against the Chicago Cubs at the historic Wrigley Field in Chicago, IL. This thrilling encounter promises to be a treat for baseball fans and bettors alike. Our picks suggest that the Cubs hold a slight edge with a predicted score of 4.8 to 3.9, favoring the Cubs in a tight matchup. The probability of the Cubs covering the spread is 44.56%, while Tampa Bay has a 55.44% chance to cover their spread. The predicted total score is 8.7, leaning towards an over 7.5 bet.
Both teams have had fluctuating performances, but the Cubs have been slightly more consistent in recent games. They boast a strong home advantage at Wrigley Field, where their hitters have performed well against righthanded pitchers, a crucial factor given the starting pitcher for Tampa Bay is righthanded. Our betting tips highlight the Cubs' advantage in this aspect, making them a favorable pick for this matchup.
Our prediction model has been profitable in the last 10 games, with a 6-4 win record in the American Totals market. This suggests a high EV for the Cubs in upcoming games. For more in-depth analysis and picks, check out our MLB picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and capitalize on the edge.
![]() CLEP. Messick (L) 13-1120% -147Bookmaker | |||||||
MIAC. Paddack (R) 11-1226% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1119% -106BetAnything | |||||||
TBS. Matz (L) 12-1072% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1351% -121Bet105 | |||||||
NYMN. McLean (R) 7-1522% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-915% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1479% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1379% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1425% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-912% -142Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |