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The Cleveland Guardians are set to face off against the Chicago White Sox on September 13, 2025, at Progressive Field in Cleveland, OH. This MLB showdown promises excitement for baseball fans and sports bettors alike. Our predictions indicate a slight edge for Cleveland with a predicted score of 3.66 over Chicago's 3.81. Cleveland's home advantage might play a crucial role, especially given their higher probability of covering the spread at 64.61%. The game will be broadcasted on CHSN, ensuring fans don't miss a moment of this thrilling encounter. The Guardians have shown resilience in recent games, while the White Sox have had mixed results. Our prediction model has been profitable, with a solid hit rate in recent games. For those looking to make informed bets, consider our betting tips and parlays. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Check out our MLB picks for more insights.
![]() CLEP. Messick (L) 13-1118% -145Bookmaker | |||||||
MIAC. Paddack (R) 11-1224% -111BetOnline | |||||||
![]() DETK. Montero (R) 12-1119% -107BetOnline | |||||||
TBS. Matz (L) 12-1068% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1348% -121Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-916% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -117Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1477% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1378% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1423% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |