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Get ready for an exciting MLB matchup as the Cincinnati Reds take on the St. Louis Cardinals at Busch Stadium in St. Louis, MO, on September 16, 2025. This game promises to be a thrilling encounter with both teams eager to make their mark. The Reds are predicted to edge out the Cardinals with a predicted score of 4.1 to 3.8. While Cincinnati's recent performance against right-handed pitchers has been commendable, the Cardinals will look to capitalize on their home advantage. Our picks suggest a close game, but Cincinnati holds a slight edge, making them a smart bet. The predicted total score of 7.9 suggests betting under 8 could be a winning move, especially with a 56% hit rate on unders in recent games. Tune in on FD Sports Network to catch all the action live. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Check out our MLB picks page for more insights and predictions.
![]() CLEP. Messick (L) 13-1118% -144Bookmaker | |||||||
MIAC. Paddack (R) 11-1224% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1119% -106BetAnything | |||||||
TBS. Matz (L) 12-1070% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1346% -121Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-915% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -118Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1480% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1378% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1423% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |