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Get ready for an exciting MLB showdown as the Cleveland Guardians take on the Detroit Tigers on September 23, 2025. This thrilling game will be held at Progressive Field in Cleveland, OH. Fans can catch the action live on CLEG. The Guardians come into this match as underdogs with a Moneyline of +135, while the Tigers are slightly favored at -160, according to Caesars. The run line is set at +1.5 -140 for Cleveland and -1.5 +118 for Detroit. The over/under is pegged at 6.5, with odds of -110 for both options.
The Guardians will look to capitalize on their strong away performance, while the Tigers aim to maintain their home dominance. With the odds slightly favoring Detroit, bettors might find value in exploring the betting lines. For those looking to make informed bets, understanding the movement in odds can provide an edge. Opening odds have shifted slightly, indicating a competitive matchup. Get the latest insights and make your betting decisions wisely by visiting our MLB odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
MIAJ. Junk (R) 11-1345% -135BetOnline | |||||||
![]() CLET. Bibee (R) 14-1120% -147Bookmaker | |||||||
TBN. Martinez (R) 12-1159% -133Bet105 | |||||||
KCM. Wacha (R) 8-166% -129Bet105 | |||||||
LAAJ. Soriano (R) 11-1422% -142BetAnything | |||||||
SEAL. Gilbert (R) 10-1536% -175BetOnline | |||||||
![]() DETC. Mize (R) 12-1285% -129BetOnline | |||||||
WSHZ. Littell (R) 11-1396% +133Bookmaker | |||||||
BOSR. Suarez (L) 9-1479% +126Everygame | |||||||
NYMC. Holmes (R) 7-168% -140Heritage | |||||||
![]() CHCM. Boyd (L) 14-924% -162Bet105 | |||||||
![]() TEXJ. Leiter (R) 12-1157% +102Bet105 | |||||||
![]() COLT. Sugano (R) 9-1589% +140Everygame | |||||||
![]() AZE. Rodriguez (L) 13-1011% -136Heritage | |||||||
SFT. Mahle (R) 10-1392% +184BetOnline |