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Before the big clash between the Detroit Tigers and Cleveland Guardians, anticipation is building for the October 2, 2025, MLB showdown at Progressive Field in Cleveland, OH. Both teams are tied 1-1 in the series, making this game a critical decider. Our picks suggest a slight edge for the Detroit Tigers, with a predicted score of 4.8 against Cleveland’s 3.3. The game will be broadcasted on ESPN networks, offering a thrilling watch for baseball fans and bettors alike.
Historically, the Tigers have shown stronger performance against right-handed pitchers, a factor that could play into their favor. The Guardians, however, have a robust home record, which they will look to leverage. Our prediction model has been profitable in the last 10 games, especially in the point spread market, where it has shown a high hit rate. This game’s best bet is on the Tigers to win, with a significant EV of 14.5%.
For those looking to make informed betting decisions, our MLB picks page Discover more MLB insights offers comprehensive predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook to profit off the edge.
![]() CLEP. Messick (L) 13-1118% -145Bookmaker | |||||||
MIAC. Paddack (R) 11-1224% -111BetOnline | |||||||
![]() DETK. Montero (R) 12-1125% -107BetOnline | |||||||
TBS. Matz (L) 12-1069% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1348% -121Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-916% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -117Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1378% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1423% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1392% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |