- Run Line
- Money
- Total
- Merged
The upcoming MLB game on June 21, 2026, features the Cleveland Guardians visiting the Houston Astros at Daikin Park in Houston, TX. Broadcasted on SCHN, this matchup offers intriguing betting lines with the Astros favored on the run line at -1.5 +153 compared to the Guardians at +1.5 -175. The moneyline odds have shifted slightly, indicating market confidence in Houston. Totals are set at 9 runs with the under favored at -125. These odds reflect strategic considerations for bettors analyzing the Guardians vs Astros game. For detailed league odds, visit the MLB odds page.
![]() DETF. Valdez (L) 33-44100% +120Everygame | |||||||
TBD. Rasmussen (R) 43-310% -185BetOnline | |||||||
MIAT. Phillips (R) 40-3825% -121BetOnline | |||||||
WSHF. Griffin (L) 40-38- -111MyBookie | |||||||
![]() TORS. Bieber (R) 38-39- -116BetOnline | |||||||
CINB. Singer (R) 37-3987% +145Everygame | |||||||
NYMK. Senga (R) 34-43100% +110Everygame | |||||||
![]() CWSA. Kay (L) 39-3725% +105Everygame | |||||||
![]() MINZ. Matthews (R) 38-41100% +140Everygame | |||||||
STLA. Pallante (R) 41-3440% -138BetOnline | |||||||
![]() COLR. Feltner (R) 30-48100% +115Everygame | |||||||
LAAS. Aldegheri (L) 32-4750% +150Everygame | |||||||
![]() SDM. King (R) 39-37- -102BetOnline |