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The Cleveland Guardians are set to face the San Diego Padres in an exciting MLB matchup on March 31, 2025, at PETCO Park. The San Diego Padres are favored to win with a moneyline of -135, while the Cleveland Guardians stand at +115. The opening odds had the Padres at -125 and the Guardians at +105, showing a slight shift towards the Padres. The point spread is at -1½ +158 for the Padres, indicating a strong probability of winning by over a point. For bettors, this game offers intriguing opportunities with the current odds reflecting the Padres' home advantage. Explore the latest MLB Odds for more insights into this thrilling encounter.
![]() CLEP. Messick (L) 13-1118% -145Bookmaker | |||||||
MIAC. Paddack (R) 11-1223% -110Bet105 | |||||||
![]() DETK. Montero (R) 12-1127% -107Bet105 | |||||||
TBS. Matz (L) 12-1069% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1377% +138Bookmaker | |||||||
BOSC. Early (L) 9-1349% -122Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-916% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -117Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1479% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1376% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1422% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1392% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |