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The MLB matchup between the Cleveland Guardians and St. Louis Cardinals is scheduled for April 15, 2026, at Busch Stadium in St. Louis, MO. This game will be broadcast on the Cardinals' local station. Our picks favor the Cardinals with a predicted score of 4 to 3.9 and a 66.3% probability of covering the +1.5 spread. The under 8.5 total is also favored with a 62% hit rate and positive EV. Both teams face a right-handed starting pitcher; the Cardinals' hitters perform slightly better against righties, influencing our betting tips. Our prediction model has shown strength in point spread markets recently, winning 6 of the last 10 games, indicating promising bets for this event. For more detailed analysis, visit our MLB picks and predictions.
BALK. Bradish (R) 9-856% -133Bet105 | |||||||
STLD. May (R) 9-853% -101Bookmaker | |||||||
![]() MINS. Woods Richardson (R) 11-752% +115Everygame | |||||||
PHIJ. Luzardo (L) 8-931% -132BetOnline | |||||||
CINR. Lowder (R) 10-729% -102BetAnything | |||||||
PITM. Montgomery (L) 10-723% -172BetOnline | |||||||
![]() DETJ. Flaherty (R) 8-950% -122BetOnline | |||||||
NYYL. Gil (R) 9-827% -174BetOnline | |||||||
ATLB. Elder (R) 11-711% -165Everygame | |||||||
![]() CWSS. Burke (R) 6-1180% +106Heritage | |||||||
MILC. Patrick (R) 8-833% +115Bet105 | |||||||
HOUS. Arrighetti (R) 7-1117% -180Everygame | |||||||
![]() ATHJ. Ginn (R) 9-867% -115BetOnline | |||||||
![]() SDR. Vásquez (R) 11-629% -107BetAnything | |||||||
LADS. Ohtani (R) 13-424% -194Bet105 |