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The upcoming MLB showdown on September 26, 2025, features the Houston Astros taking on the L.A. Angels Angels at Angel Stadium in Anaheim, CA. This exciting matchup is set to be broadcasted on schn and fdsw, offering fans a thrilling night of baseball action. The Astros, led by a strong lineup, are looking to maintain their favorite status with a Moneyline of -145, according to Caesars. Meanwhile, the Angels are the underdogs with a Moneyline of +122. The run line is set at -1.5 -110 for the Astros and +1.5 -110 for the Angels, showing a competitive edge. With the over/under set at 9.0, bettors can expect a potentially high-scoring game. As the Astros aim to secure their dominance, the Angels will be striving to defend their home turf. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Stay updated with the latest odds and changes on our MLB odds page.
![]() CLEP. Messick (L) 13-1122% -133Everygame | |||||||
MIAC. Paddack (R) 11-1230% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1116% -106BetAnything | |||||||
TBS. Matz (L) 12-1076% +103BetOnline | |||||||
WSHF. Griffin (L) 10-1373% +127Bet105 | |||||||
BOSC. Early (L) 9-1351% -121Everygame | |||||||
NYMN. McLean (R) 7-1525% -152BetOnline | |||||||
![]() CHCS. Imanaga (L) 13-916% -125Bookmaker | |||||||
KCK. Bubic (L) 7-1612% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +133Bookmaker | |||||||
LAAJ. Kochanowicz (R) 11-1380% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1426% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-913% -142Bet105 | |||||||
SFL. Roupp (R) 9-1390% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -143BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |