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The Seattle Mariners face the Houston Astros on May 12, 2026, at Daikin Park in Houston, TX, in this MLB regular-season game broadcast on schn. Our picks favor Seattle with a predicted score of 4.53 to Houston's 3.71, and a point spread leaning towards Houston +1.5, which has a 57.7% probability of covering. Seattle's hitters show stronger performance against right-handed pitchers, which aligns with Houston's likely pitching setup, influencing our betting tips. Our model has demonstrated profitable results in the last 10 games, especially on point spread markets with a high EV and a strong hit rate. For comprehensive MLB insights, visit MLB picks and predictions.
![]() MINC. Prielipp (L) 32-390% -105BetOnline | |||||||
![]() TORK. Gausman (R) 34-36- +115Everygame | |||||||
PITB. Chandler (R) 35-35- -125BetOnline | |||||||
BALT. Gibson (R) 34-37- -125BetOnline | |||||||
WSHC. Cavalli (R) 35-35- -107BetOnline | |||||||
NYMS. Manaea (L) 31-38- -105BetOnline | |||||||
CINR. Lowder (R) 32-36- +123Everygame | |||||||
![]() CLEJ. Cantillo (L) 38-33100% +135Everygame | |||||||
BOSR. Suarez (L) 28-39- -115BetOnline | |||||||
![]() CWSS. Burke (R) 37-31- +179Bookmaker | |||||||
MILS. Drohan (L) 42-25- -136BetOnline | |||||||
KCN. Cameron (L) 28-42- -119BetOnline | |||||||
SFT. McDonald (R) 28-42- +114Everygame | |||||||
![]() ATHJ. Estes (R) 34-350% -163BetOnline | |||||||
LAAJ. Soriano (R) 28-42- +113BetOnline |