- Run Line
- Money
- Total
- Merged
The upcoming MLB regular season game between the St. Louis Cardinals and Houston Astros is scheduled for April 17, 2026, at 8:10 PM ET at Daikin Park in Houston, TX. Broadcasted on schn, this matchup features a retractable dome venue favoring consistent playing conditions. Our data-driven picks suggest a competitive game with a predicted score of St. Louis 4.40 to Houston 4.06, favoring the Cardinals on the spread. Houston's right-handed starting pitcher faces a Cardinals lineup with moderate success against righties, influencing our betting tips. Our model shows a 55.4% hit rate with positive EV on under 8.5 total runs in recent games, reinforcing an under bet. For detailed analysis and more MLB picks, visit our MLB Picks and Predictions.
TBC. Legumina (R) 44-3344% -135BetAnything | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4659% -123Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -108BetAnything | |||||||
WSHC. Cavalli (R) 41-4070% +163Bookmaker | |||||||
![]() TORK. Gausman (R) 39-4119% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4670% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |