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The upcoming MLB game on May 16, 2026, features the Kansas City Royals vs St. Louis Cardinals at Busch Stadium in St. Louis, MO. Broadcasted on royl and card, the match predicts a close contest with the Cardinals slightly favored, projecting a 3.89 to 3.76 scoreline. Our picks favor Kansas City +1.5 with a 64.8% cover probability and a positive EV of 0.5%, supported by a strong 64.8% hit rate in recent spreads. The predicted total score is 7.65, favoring under 9 bets with a 67.3% hit rate and 15.1% EV. Hitters' performance against right-handed pitching influences these predictions. For comprehensive MLB betting tips, visit MLB picks and predictions.
CINN. Lodolo (L) 35-370% +119BetOnline | |||||||
PHIA. Painter (R) 40-33- -109BetOnline | |||||||
WSHZ. Littell (R) 39-35- -126Bet105 | |||||||
HOUP. Lambert (R) 34-41- +100BetOnline | |||||||
LADS. Ohtani (R) 47-27- -175BetOnline | |||||||
![]() AZE. Rodriguez (L) 37-36- -160Bookmaker | |||||||
BOSJ. Bennett (L) 29-41- -122BetOnline | |||||||
NYYC. Rodón (L) 44-27- -180Bet105 | |||||||
ATLJ. Ritchie (R) 46-25- -135BetOnline | |||||||
MILB. Sproat (R) 44-260% -115Everygame | |||||||
![]() CHCJ. Assad (R) 38-36- -180BetOnline | |||||||
SEAG. Kirby (R) 38-36- -139Bet105 | |||||||
![]() ATHA. Civale (R) 36-37- +104BetOnline |