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The upcoming MLB game between the St. Louis Cardinals and Miami Marlins is scheduled for April 22, 2026, at loanDepot park in Miami, FL. Broadcasted on miam, this matchup features the Cardinals as slight favorites with a predicted score of 4.01 against Miami's 4.08. Our picks indicate St. Louis covering the +1.5 spread with a 64.9% probability and an EV of 0.7%. The total score prediction leans under 8.5 runs with a 59% hit rate and 8.5% EV. Notably, Miami's hitters have moderate performance against right-handed pitching, which aligns with current betting tips favoring under bets. Our prediction model has achieved a positive hit rate in recent games, especially in point spread markets, supporting these picks. Explore more detailed MLB picks for this season on MLB Picks and Predictions.
TBC. Legumina (R) 44-3342% -135BetAnything | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4657% -122Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -104Bookmaker | |||||||
WSHC. Cavalli (R) 41-4070% +155Everygame | |||||||
![]() TORK. Gausman (R) 39-4118% -126Heritage | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4668% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |