N.Y. Yankees vs Toronto Blue Jays: Game Preview & Betting Insights

As the N.Y. Yankees face off against the Toronto Blue Jays on July 22, 2025, at the Rogers Centre in Toronto, ON, fans and bettors alike are eager to see how this matchup unfolds. The Blue Jays, playing at their home stadium with a retractable dome, have the advantage with a strong home record, which you can see on our MLB standings page. In their last matchup on July 21st, the Blue Jays emerged victorious with a final score of 4-1.

The Yankees will be sending Cam Schlittler (R) to the mound, who holds a 5.063 ERA, while the Blue Jays will counter with Max Scherzer (R) and his 4.696 ERA. This game, broadcasted on Amazon Prime Vid, is set to start at 7:07 PM ET. The Blue Jays are favored with 2way odds at -130 compared to the Yankees' +110, and the point spread is favoring Toronto at -1.5. The total points over/under is set at 9.

With key players like Giancarlo Stanton and Aaron Judge for the Yankees, and Vladimir Guerrero Jr. and Bo Bichette for the Blue Jays, both teams bring formidable lineups. However, the Blue Jays' superior fielding and hitting stats give them an edge. Keep an eye on the Blue Jays' strategic advantage at home, where they excel with a 36-16 record.