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The clash between the Pittsburgh Pirates and St. Louis Cardinals on August 25, 2025, at Busch Stadium in St. Louis, MO, is set to be a thrilling MLB encounter. The Pirates come into this game with a strategic advantage, having won 6 out of their last 10 games, particularly excelling in 2-way bets. The Cardinals, however, are looking to capitalize on their home field advantage despite a recent loss streak. Our prediction model suggests a close game with the Cardinals edging out the Pirates with a predicted score of 5.12 to 4.03. Bettors should consider the under 8.5 market, which has shown a 52.8% hit rate. Additionally, the Pirates' hitters have shown better performance against right-handed pitchers, which could be pivotal in their strategy. Catch the action live on Sportsnet PT. For more insights and detailed picks, check out our MLB picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() CLEP. Messick (L) 13-1120% -147Bookmaker | |||||||
MIAC. Paddack (R) 11-1226% -109BetAnything | |||||||
![]() DETK. Montero (R) 12-1119% -106BetAnything | |||||||
TBS. Matz (L) 12-1072% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bet105 | |||||||
BOSC. Early (L) 9-1351% -121Bet105 | |||||||
NYMN. McLean (R) 7-1522% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-915% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -116Bet105 | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1479% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1379% -108Bookmaker | |||||||
SEAL. Castillo (R) 10-1425% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-912% -142Bet105 | |||||||
SFL. Roupp (R) 9-1391% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |