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The St. Louis Cardinals and Pittsburgh Pirates are set to clash at Busch Stadium in St. Louis, MO on August 26, 2025. This MLB showdown promises to be a thrilling contest with plenty at stake. The Cardinals, coming off a close 7-6 victory, will look to continue their winning momentum against the Pirates. Our top pick for this game is the Cardinals to win, with a predicted score of 5-3, supported by strong recent performances and a favorable home advantage.
Our prediction model favors the Cardinals, with a 65% probability of victory and an EV of 8.5%. The Pirates, however, are not to be underestimated, as they have shown resilience in recent games. The over/under is set at 8, with our prediction suggesting a total score of 9, making the over a potentially profitable bet. Explore more MLB picks to find additional insights.
For those interested in betting, the best odds for the Cardinals can be found at SugarHouse. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook.
![]() CLEP. Messick (L) 13-1118% -145Bookmaker | |||||||
MIAC. Paddack (R) 11-1224% -110Bet105 | |||||||
![]() DETK. Montero (R) 12-1125% -107Bet105 | |||||||
TBS. Matz (L) 12-1069% +101BetOnline | |||||||
WSHF. Griffin (L) 10-1376% +138Bookmaker | |||||||
BOSC. Early (L) 9-1348% -122Bet105 | |||||||
NYMN. McLean (R) 7-1521% -153Everygame | |||||||
![]() CHCS. Imanaga (L) 13-916% -127BetOnline | |||||||
KCK. Bubic (L) 7-1613% -117Bookmaker | |||||||
![]() TEXK. Rocker (R) 11-1150% -106Bet105 | |||||||
![]() COLJ. Herget (R) 9-1478% +130Everygame | |||||||
LAAJ. Kochanowicz (R) 11-1378% -109BetAnything | |||||||
SEAL. Castillo (R) 10-1423% -153Everygame | |||||||
![]() AZM. Kelly (R) 13-911% -143Bet105 | |||||||
SFL. Roupp (R) 9-1392% +157Everygame | |||||||
MIAJ. Junk (R) 11-12- -121BetOnline | |||||||
![]() CLET. Bibee (R) 13-11- -128MyBookie | |||||||
TBN. Martinez (R) 12-10- -125BetOnline | |||||||
KCM. Wacha (R) 7-16- -125MyBookie | |||||||
LAAJ. Soriano (R) 11-13- -141BetOnline | |||||||
SEAL. Gilbert (R) 10-14- -185BetOnline | |||||||
![]() DETC. Mize (R) 12-11- -130BetOnline | |||||||
WSHZ. Littell (R) 10-13- +134BetOnline | |||||||
BOSR. Suarez (L) 9-13- +119Heritage | |||||||
![]() COLT. Sugano (R) 9-14- - | |||||||
![]() AZE. Rodriguez (L) 13-9- -138BetOnline | |||||||
SFT. Mahle (R) 9-13- +174Heritage |